N~1~-(2-Methylphenyl)glycinamide

Base Information

Chemical Name:N~1~-(2-Methylphenyl)glycinamide
CAS No.:145133-90-0
Molecular Formula:C9H12N2O
Molecular Weight:164.207
Hs Code.:
DSSTox Substance ID:DTXSID50388582
Nikkaji Number:J519.734A
Wikidata:Q82183637
Mol file:145133-90-0.mol

Synonyms:145133-90-0;N~1~-(2-METHYLPHENYL)GLYCINAMIDE;2-amino-N-(o-tolyl)acetamide;2-amino-N-(2-methylphenyl)acetamide;N1-(2-Methylphenyl)glycinamide;N-(2-methylphenyl)glycinamide;SCHEMBL7284784;DTXSID50388582;STL183971;N-(2-Methylphenyl)-2-aminoacetamide;AKOS000190261;n1-(2-Methylphenyl)glycinamide x1hbr;SB75924;CS-0334065;N~1~-(2-Methylphenyl)glycinamide, AldrichCPR

Suppliers and Price of N~1~-(2-Methylphenyl)glycinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N~1~-(2-Methylphenyl)glycinamide

Chemical Property:

Vapor Pressure:0.000128mmHg at 25°C
Boiling Point:334.4°C at 760 mmHg
Flash Point:156°C
Density:1.152g/cm³
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:164.094963011
Heavy Atom Count:12
Complexity:159

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1NC(=O)CN

Technology Process of N~1~-(2-Methylphenyl)glycinamide

There total 8 articles about N~1~-(2-Methylphenyl)glycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 37394-93-7
2-chloro-N-(2-methylphenyl)acetamide

: 145133-90-0
2-amino-N-(o-tolyl)acetamide

Guidance literature:: With ammonium hydroxide; at 60 ℃; for 6h; Inert atmosphere;
DOI:10.1016/j.ejmech.2020.112257

Reference yield:

: 95-53-4
o-toluidine

: 145133-90-0
2-amino-N-(o-tolyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: 4-methyl-morpholine; isobutyl chloroformate / N,N-dimethyl-formamide / 0.17 h / -20 °C

1.2: 4 h / 20 °C

2.1: trifluoroacetic acid / 0.5 h / 20 °C

With 4-methyl-morpholine; trifluoroacetic acid; isobutyl chloroformate; In N,N-dimethyl-formamide;
DOI:10.1007/s00044-013-0474-y