Dimethyl 2-(4-chloro-2-nitrophenyl)malonate

Base Information

Chemical Name:Dimethyl 2-(4-chloro-2-nitrophenyl)malonate
CAS No.:147124-32-1
Molecular Formula:C11H10ClNO6
Molecular Weight:287.656
Hs Code.:2917399090
DSSTox Substance ID:DTXSID00369447
Wikidata:Q82156523
Mol file:147124-32-1.mol

Synonyms:dimethyl 2-(4-chloro-2-nitrophenyl)malonate;147124-32-1;dimethyl 2-(4-chloro-2-nitrophenyl)propanedioate;Maybridge1_006222;Oprea1_429454;SCHEMBL624054;1,3-dimethyl 2-(4-chloro-2-nitrophenyl)propanedioate;HMS559C18;DTXSID00369447;XNQGJNNDVKLNQO-UHFFFAOYSA-N;XFA12432;CCG-44194;MFCD00179451;AKOS005070715;dimethyl 4-chloro-2-nitrophenylmalonate;dimethyl2-(4-chloro-2-nitrophenyl)malonate;CS-0213435;FT-0680472;5W-0075;A884459;J-520352;SR-01000634045-1;2-(4-Chloro-2-nitro-phenyl)-malonic acid dimethyl ester

Suppliers and Price of Dimethyl 2-(4-chloro-2-nitrophenyl)malonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dimethyl2-(4-chloro-2-nitrophenyl)malonate
1g
$ 145.00

Matrix Scientific
Dimethyl 2-(4-chloro-2-nitrophenyl)malonate >95%
5g
$ 258.00

Matrix Scientific
Dimethyl 2-(4-chloro-2-nitrophenyl)malonate >95%
1g
$ 69.00

Matrix Scientific
Dimethyl 2-(4-chloro-2-nitrophenyl)malonate >95%
500mg
$ 45.00

Crysdot
Dimethyl2-(4-chloro-2-nitrophenyl)malonate 95+%
10g
$ 412.00

American Custom Chemicals Corporation
DIMETHYL-2-(4-CHLORO-2-NITROPHENYL)MALONATE 95.00%
5MG
$ 505.05

AK Scientific
Dimethyl2-(4-chloro-2-nitrophenyl)malonate
5g
$ 398.00

Total 14 raw suppliers

Chemical Property of Dimethyl 2-(4-chloro-2-nitrophenyl)malonate

Chemical Property:

Melting Point:83-85°
Boiling Point:387.1±37.0 °C(Predicted)
PKA:9.42±0.46(Predicted)
PSA：98.42000
Density:1.415±0.06 g/cm3(Predicted)
LogP:2.20100
Storage Temp.:Room temperature.
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:287.0196647
Heavy Atom Count:19
Complexity:353

Purity/Quality:

97% ^*data from raw suppliers

Dimethyl2-(4-chloro-2-nitrophenyl)malonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C(C1=C(C=C(C=C1)Cl)[N+](=O)[O-])C(=O)OC

Technology Process of Dimethyl 2-(4-chloro-2-nitrophenyl)malonate

There total 3 articles about Dimethyl 2-(4-chloro-2-nitrophenyl)malonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-59-8
malonic acid dimethyl ester

: 89-61-2
2,5-dichloronitrobenzene

: 147124-32-1
dimethyl (4-chloro-2-nitrophenyl)malonate

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1) DMSO, 100 deg C, 40 min, 2a) RT, 30 min, 2b) 100 deg C, 1 h;
DOI:10.1055/s-1993-25790

Reference yield:

: 345-18-6
2-fluoro-5-chloronitrobenzene

: 108-59-8
malonic acid dimethyl ester

: 147124-32-1
dimethyl (4-chloro-2-nitrophenyl)malonate

Guidance literature:: malonic acid dimethyl ester; With potassium tert-butylate; In N,N-dimethyl-formamide; at 90 ℃; for 0.166667h;

2-fluoro-5-chloronitrobenzene; In N,N-dimethyl-formamide; at 90 ℃; for 2h;
DOI:10.1021/ol200652j

Reference yield:

: 108-59-8
malonic acid dimethyl ester

: 147124-32-1
dimethyl (4-chloro-2-nitrophenyl)malonate

Guidance literature:: malonic acid dimethyl ester; With potassium tert-butylate; In N,N-dimethyl-formamide; at 90 ℃; for 0.166667h;

2-halo-5-chloro-1-nitrobenzene; In N,N-dimethyl-formamide; at 90 ℃;
DOI:10.1002/anie.202105282