N-BUTYRYL-L-HOMOCYSTEINE THIOLACTONE

Base Information

• Chemical Name: N-BUTYRYL-L-HOMOCYSTEINE THIOLACTONE
• CAS No.: 202284-85-3
• Molecular Formula: C₈H₁₃NO₂S
• Molecular Weight: 187.263
• Mol file: 202284-85-3.mol

Synonyms:N-BUTYRYL-L-HOMOCYSTEINE THIOLACTONE;N-butyryl-L-Homocysteine thiolactone Exclusive

Chemical Property of N-BUTYRYL-L-HOMOCYSTEINE THIOLACTONE

Chemical Property:

• Boiling Point: 424.6±34.0 °C(Predicted)
• PKA: 14.62±0.20(Predicted)
• PSA: 71.47000
• Density: 1.17±0.1 g/cm3(Predicted)
• LogP: 1.32570

Purity/Quality:

95% ^*data from raw suppliers

N-butyryl-L-Homocysteine thiolactone ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-BUTYRYL-L-HOMOCYSTEINE THIOLACTONE

There total 2 articles about N-BUTYRYL-L-HOMOCYSTEINE THIOLACTONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

L-homocysteine thiolactone (2338-04-7,10593-85-8,14007-10-4,130548-06-0) + butyric acid (107-92-6) → (S)-N-butyryl homocysteine thiolactone (202284-85-3,39837-08-6)

Guidance literature:

With N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In water;

DOI:10.1246/cl.2001.314

Reference yield:

L-homocysteine thiolactone hydrochloride (31828-68-9) + butyric acid (107-92-6) → (S)-N-butyryl homocysteine thiolactone (202284-85-3,39837-08-6)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 14h;

DOI:10.1016/j.bmc.2011.06.071

upstream raw materials:

L-homocysteine thiolactone

butyric acid

L-homocysteine thiolactone hydrochloride