N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE

Base Information

Chemical Name:N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE
CAS No.:869355-04-4
Molecular Formula:C₁₃H₁₈N₆O₄
Molecular Weight:322.324
Hs Code.:
Mol file:869355-04-4.mol

Synonyms:N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE;N2-(DMF)-3'-DEOXYGUANOSINE

Suppliers and Price of N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE 95.00%
5MG
$ 495.63

Total 4 raw suppliers

Chemical Property of N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE

Chemical Property:

PSA：128.86000
LogP:-1.01830

Purity/Quality:

97% ^*data from raw suppliers

N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE

There total 13 articles about N2-(DIMETHYLAMINOMETHYLIDENE)-3'-DEOXYGUANOSINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: Acetic acid (2R,3R,5S)-2-[2-(dimethylamino-methyleneamino)-6-oxo-1,6-dihydro-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3-yl ester

: 869355-04-4
N'-[9-((2R,3R,5S)-3-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-N,N-dimethyl-formamidine

Guidance literature:: With ammonium hydroxide; In methanol;
DOI:10.1016/S0040-4039(00)02041-4

Reference yield: 92.0%

: 4637-24-5
N,N-dimethyl-formamide dimethyl acetal

: 3608-58-0
3'-deoxyguanosine

: 869355-04-4
N'-[9-((2R,3R,5S)-3-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-N,N-dimethyl-formamidine

Guidance literature:: In methanol;
DOI:10.1080/07328319708006156

Reference yield:

: 17331-16-7
N²-(dimethylaminomethylene)guanosine

: 869355-04-4
N'-[9-((2R,3R,5S)-3-Hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-N,N-dimethyl-formamidine

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent

2: 83 percent / H₂O / acetonitrile / 0 °C

3: 91 percent / tri-n-butyltin hydride; 2,2'-azobisisoburtyronitrile / toluene / 2 h / 95 °C

4: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0 °C

5: 100 percent / aq. ammonia / methanol

With ammonium hydroxide; 2,2'-azobis(isobutyronitrile); tetrabutyl ammonium fluoride; water; tri-n-butyl-tin hydride; In tetrahydrofuran; methanol; toluene; acetonitrile;
DOI:10.1016/S0040-4039(00)02041-4