5-Methoxy-2-methylindoline

Base Information

Chemical Name:5-Methoxy-2-methylindoline
CAS No.:41568-27-8
Molecular Formula:C10H13NO
Molecular Weight:163.21632
Hs Code.:
DSSTox Substance ID:DTXSID20444947,DTXSID30902644
Nikkaji Number:J1.293.003H
Mol file:41568-27-8.mol

Synonyms:5-Methoxy-2-methylindoline;41568-27-8;5-methoxy-2-methyl-2,3-dihydro-1H-indole;2-Methyl-5-methoxyindoline;NoName_3183;2,3-Dihydro-5-methoxy-2-methyl-1H-indole;SCHEMBL11087883;DTXSID20444947;DTXSID30902644;AKOS022300075;FT-0671269;EN300-822194;Z1255421552

Suppliers and Price of 5-Methoxy-2-methylindoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
5-Methoxy-2-methylindoline
100mg
$ 425.00

TRC
5-Methoxy-2-methylindoline
100mg
$ 145.00

AK Scientific
5-Methoxy-2-methylindoline
2.5g
$ 2404.00

AK Scientific
5-Methoxy-2-methylindoline
250mg
$ 681.00

AccelPharmtech
2,3-dihydro-5-methoxy-2-methyl-1H-Indole 97.00%
25G
$ 5120.00

AccelPharmtech
2,3-dihydro-5-methoxy-2-methyl-1H-Indole 97.00%
5G
$ 2750.00

AccelPharmtech
2,3-dihydro-5-methoxy-2-methyl-1H-Indole 97.00%
1G
$ 2370.00

Total 2 raw suppliers

Chemical Property of 5-Methoxy-2-methylindoline

Chemical Property:

PSA：21.26000
LogP:2.18970
Storage Temp.:Hygroscopic, Refrigerator, under inert atmosphere
Solubility.:Chloroform, DMSO, Methanol (Slightly)
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:163.099714038
Heavy Atom Count:12
Complexity:160

Purity/Quality:

98% ^*data from raw suppliers

5-Methoxy-2-methylindoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2=C(N1)C=CC(=C2)OC
Uses 5-Methoxy-2-methylindoline is used in the preparation of indole-3-acetamides, inhibitors of phospholipase A2. 2,3-dihydro-5-Methoxy-2-Methyl-1H-Indole is used in the preparation of indole-3-acetamides, inhibitors of phospholipase A2.

Technology Process of 5-Methoxy-2-methylindoline

There total 5 articles about 5-Methoxy-2-methylindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1076-74-0
5-methoxy-2-methyl-1H-indole

: 41568-27-8
(±)-5-methoxy-2-methylindoline

Guidance literature:: With sodium cyanoborohydride; In acetic acid; at 20 ℃; for 12h;
DOI:10.1021/ja0657859

Reference yield: 85.0%

: 71954-46-6
N-allyl-4-methoxyaniline

: 41568-27-8
(±)-5-methoxy-2-methylindoline

Guidance literature:: Zn⁽²⁺⁾ montmorillonite; for 0.05h; microwave irradiation;

Reference yield:

: 51-66-1
4-methoxyacetanilide

: 41568-27-8
(±)-5-methoxy-2-methylindoline

Guidance literature:: Multi-step reaction with 3 steps

1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; silver hexafluoroantimonate; copper diacetate; silver carbonate / 1,4-dioxane / 24 h / 110 °C / Schlenk technique; Inert atmosphere

2: potassium hydroxide / tetrahydrofuran; ethanol / Reflux

3: sodium cyanoborohydride; acetic acid / 12 h / 20 °C

With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; copper diacetate; sodium cyanoborohydride; acetic acid; silver carbonate; potassium hydroxide; In tetrahydrofuran; 1,4-dioxane; ethanol;
DOI:10.1016/j.tetlet.2013.11.065