5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide

Base Information

Chemical Name:5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide
CAS No.:100331-93-9
Molecular Formula:C18H15NO3
Molecular Weight:293.322
Hs Code.:
DSSTox Substance ID:DTXSID50548265
Wikidata:Q82426908
Mol file:100331-93-9.mol

Synonyms:100331-93-9;5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide;1-(1-oxido-8-phenylmethoxyquinolin-1-ium-5-yl)ethanone;5-Acetyl-8-benzyloxyquinoline-N-oxide;SCHEMBL3311669;DTXSID50548265;WHMJVXAIEYJTCL-UHFFFAOYSA-N;5-ACETYL-8-(BENZYLOXY)QUINOLIN-1-IUM-1-OLATE;1-[8-(Benzyloxy)-1-oxo-1lambda~5~-quinolin-5-yl]ethan-1-one

Suppliers and Price of 5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Acetyl-8-(phenylmethoxy)-2-quinolineN-Oxide
100mg
$ 580.00

TRC
5-Acetyl-8-(phenylmethoxy)-2-quinolineN-Oxide
250mg
$ 1320.00

Medical Isotopes, Inc.
5-Acetyl-8-(phenylmethoxy)-2-quinolineN-Oxide
250 mg
$ 2700.00

Biosynth Carbosynth
5-Acetyl-8-(phenylmethoxy)-2-quinoline N-oxide
25 mg
$ 272.50

Biosynth Carbosynth
5-Acetyl-8-(phenylmethoxy)-2-quinoline N-oxide
10 mg
$ 149.90

Biosynth Carbosynth
5-Acetyl-8-(phenylmethoxy)-2-quinoline N-oxide
50 mg
$ 496.00

Biosynth Carbosynth
5-Acetyl-8-(phenylmethoxy)-2-quinoline N-oxide
250 mg
$ 1640.00

Biosynth Carbosynth
5-Acetyl-8-(phenylmethoxy)-2-quinoline N-oxide
100 mg
$ 901.00

AK Scientific
5-Acetyl-8-(phenylmethoxy)-2-quinolineN-Oxide
50mg
$ 719.00

AK Scientific
5-Acetyl-8-(phenylmethoxy)-2-quinolineN-Oxide
25mg
$ 417.00

Total 3 raw suppliers

Chemical Property of 5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide

Chemical Property:

Melting Point:136.5-137.5 °C
Boiling Point:526.2±58.0 °C(Predicted)
PKA:-0.50±0.30(Predicted)
PSA：51.76000
Density:1.18±0.1 g/cm3(Predicted)
LogP:4.04990
Solubility.:Methanol
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:293.10519334
Heavy Atom Count:22
Complexity:381

Purity/Quality:

98%min ^*data from raw suppliers

5-Acetyl-8-(phenylmethoxy)-2-quinolineN-Oxide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=C2C=CC=[N+](C2=C(C=C1)OCC3=CC=CC=C3)[O-]
Uses 5-Acetyl-8-(phenylMethoxy)-2-quinoline N-Oxide can be used in the preparation of phenylethanolamine derivatives as β2 adrenoreceptor agonists.

Technology Process of 5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide

There total 5 articles about 5-Acetyl-8-(phenylmethoxy)-2-quinoline N-Oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 26872-48-0
1-(8-benzyloxyquinolin-5-yl)ethanone

: 100331-93-9
5-Acetyl-8-benzyloxyquinoline-N-oxide

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In chloroform;

Reference yield:

: 148-24-3,24804-14-6
8-quinolinol

: 100331-93-9
5-Acetyl-8-benzyloxyquinoline-N-oxide

Guidance literature:: Multi-step reaction with 4 steps

1.1: 1,2-dichloro-ethane / 2.25 - 2.33 h / 30 °C

1.2: 15.25 - 16.33 h / 25 - 70 °C

1.3: 0.25 - 0.33 h / 0 - 30 °C

2.1: hydrogenchloride; water / 0.25 - 0.33 h

3.1: potassium carbonate / acetone / 14 h / Heating / reflux

4.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3.5 h / 20 - 30 °C

With hydrogenchloride; water; potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; 1,2-dichloro-ethane; acetone;

Reference yield:

: 2598-31-4
5-acetyl-8-hydroxyquinoline

: 100331-93-9
5-Acetyl-8-benzyloxyquinoline-N-oxide

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 14 h / Heating / reflux

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 3.5 h / 20 - 30 °C

With potassium carbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; acetone;