3-(Benzoyloxy)-3,6-dihydro-6-methoxy-2H-pyran-2-methanol benzoate

Base Information

• Chemical Name: 3-(Benzoyloxy)-3,6-dihydro-6-methoxy-2H-pyran-2-methanol benzoate
• CAS No.: 56248-18-1
• Molecular Formula: C₂₁H₂₀O₆
• Molecular Weight: 368.386
• Mol file: 56248-18-1.mol

Synonyms:3-(Benzoyloxy)-3,6-dihydro-6-methoxy-2H-pyran-2-methanol benzoate

Chemical Property of 3-(Benzoyloxy)-3,6-dihydro-6-methoxy-2H-pyran-2-methanol benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-(Benzoyloxy)-3,6-dihydro-6-methoxy-2H-pyran-2-methanol benzoate

There total 16 articles about 3-(Benzoyloxy)-3,6-dihydro-6-methoxy-2H-pyran-2-methanol benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 2,3-dideoxy-4,6-dihydroxy-α-D-erythro-hex-2-enopyranoside (22860-25-9) + benzoyl chloride (98-88-4) → methyl 4,6-di-O-benzoyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside (6605-37-4,56248-18-1)

Guidance literature:

With pyridine; at 0 ℃; for 0.5h;

DOI:10.1039/c004204h

Reference yield: 100.0%

methyl 2,3-dideoxy-β-D-threo-hex-2-enopyranoside + benzoyl chloride (98-88-4) → methyl 2,3-dideoxy-4,6-di-O-benzoyl-β-D-threo-hex-2-enopyranoside (56248-18-1)

Guidance literature:

With pyridine; In dichloromethane; at 0 - 21 ℃; for 24h;

DOI:10.1021/acs.joc.0c01170

Reference yield: 98.0%

methyl 4,6-di-O-acetyl-2,3-dideoxy-α-D-threo-hex-2-enopyranoside (6605-29-4) + benzoyl chloride (98-88-4) → methyl 4,6-di-O-benzoyl-2,3-dideoxy-α-D-threo-hex-2-enopyranoside (6605-38-5,56248-18-1)

Guidance literature:

methyl 4,6-di-O-acetyl-2,3-dideoxy-α-D-threo-hex-2-enopyranoside; With sodium methylate; In methanol; dichloromethane; at 20 ℃; for 2h;

benzoyl chloride; With pyridine; In tetrahydrofuran; at 20 ℃; for 20h;

DOI:10.1021/acs.orglett.6b03000

upstream raw materials:

methyl 2,3-dideoxy-4,6-dihydroxy-α-D-erythro-hex-2-enopyranoside

benzoyl chloride

methyl 2-deoxy-2-iodo-3,4-O-isopropylidene-α-D-altropyranoside

methyl 2-deoxy-2-iodo-α-D-altropyranoside