BOC-MET-ENKEPHALIN-T-BUTYL ESTER

Base Information

Chemical Name:BOC-MET-ENKEPHALIN-T-BUTYL ESTER
CAS No.:82362-16-1
Molecular Formula:C36H51N5O9S
Molecular Weight:729.895
Hs Code.:
Mol file:82362-16-1.mol

Synonyms:BOC-TYR-GLY-GLY-PHE-MET-OTBU;BOC-MET-ENKEPHALIN-T-BUTYL ESTER

Suppliers and Price of BOC-MET-ENKEPHALIN-T-BUTYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of BOC-MET-ENKEPHALIN-T-BUTYL ESTER

Chemical Property:

PSA：226.56000
LogP:4.32200
Storage Temp.:-15°C

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of BOC-MET-ENKEPHALIN-T-BUTYL ESTER

There total 10 articles about BOC-MET-ENKEPHALIN-T-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

: 82362-15-0
H-Gly-Phe-Met-OBu^t

: 75903-26-3
Boc-Tyr-Gly-N₃

: 82362-16-1
Boc-Tyr-Gly-Gly-Phe-Met-OBu^t

Guidance literature:: In N,N-dimethyl-formamide; at 4 ℃;
DOI:10.1248/cpb.30.581

Reference yield:

: 1161-13-3
N-Cbz-L-Phe

: 82362-16-1
Boc-Tyr-Gly-Gly-Phe-Met-OBu^t

Guidance literature:: Multi-step reaction with 5 steps

1: 45 percent / DCC / acetonitrile / -10 °C

2: palladium / ethanol; cyclohexene / 0.5 h / Heating

3: 59 percent / DCC, 1-hydroxybenzotriazole / acetonitrile; dimethylformamide / -10 °C

4: palladium / ethanol / 0.5 h / Heating

5: 46 percent / dimethylformamide / 4 °C

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium; In ethanol; N,N-dimethyl-formamide; acetonitrile; cyclohexene;
DOI:10.1248/cpb.30.581

Reference yield:

: 4976-72-1
tert-butyl (2S)-2-amino-4-methylsulfanylbutanoate

: 82362-16-1
Boc-Tyr-Gly-Gly-Phe-Met-OBu^t

Guidance literature:: Multi-step reaction with 5 steps

1: 45 percent / DCC / acetonitrile / -10 °C

2: palladium / ethanol; cyclohexene / 0.5 h / Heating

3: 59 percent / DCC, 1-hydroxybenzotriazole / acetonitrile; dimethylformamide / -10 °C

4: palladium / ethanol / 0.5 h / Heating

5: 46 percent / dimethylformamide / 4 °C

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; palladium; In ethanol; N,N-dimethyl-formamide; acetonitrile; cyclohexene;
DOI:10.1248/cpb.30.581