16-PHENOXY TETRANOR PROSTAGLANDIN E2

Base Information

Chemical Name:16-PHENOXY TETRANOR PROSTAGLANDIN E2
CAS No.:54382-74-0
Molecular Formula:C₂₂H₂₈O₆
Molecular Weight:388.461
Hs Code.:
Mol file:54382-74-0.mol

Synonyms:9-OXO-11ALPHA,15R-DIHYDROXY-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;16-PHENOXY TETRANOR PROSTAGLANDIN E2

Suppliers and Price of 16-PHENOXY TETRANOR PROSTAGLANDIN E2

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Cayman Chemical
16-phenoxy tetranor Prostaglandin E2 ≥98%
10mg
$ 408.00

Cayman Chemical
16-phenoxy tetranor Prostaglandin E2 ≥98%
5mg
$ 230.00

Cayman Chemical
16-phenoxy tetranor Prostaglandin E2 ≥98%
1mg
$ 51.00

American Custom Chemicals Corporation
16-PHENOXY TETRANOR PROSTAGLANDIN E2 95.00%
5MG
$ 497.81

AK Scientific
(Z)-7-[(2R,3R)-3-Hydroxy-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]hept-5-enoicacid
10mg
$ 650.00

Total 8 raw suppliers

Chemical Property of 16-PHENOXY TETRANOR PROSTAGLANDIN E2

Chemical Property:

PSA：104.06000
LogP:2.74980

Purity/Quality:

99% ^*data from raw suppliers

16-phenoxy tetranor Prostaglandin E2 ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description 16-phenoxy tetranor PGE2 is the free acid form of sulprostone formed by the hydrolysis of the methylsulfonamide bond. 16-phenoxy tetranor PGE2 is a minor metabolite of sulprostone found in human plasma after parenteral administration of the drug.

Technology Process of 16-PHENOXY TETRANOR PROSTAGLANDIN E2

There total 4 articles about 16-PHENOXY TETRANOR PROSTAGLANDIN E2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51638-93-8
(3aR,4R,5R,6aS)-5-Hydroxy-4-((E)-(R)-3-hydroxy-4-phenoxy-but-1-enyl)-hexahydro-cyclopenta[b]furan-2-one

: 54382-74-0
16-phenoxy-ω-tetranor-PGE₂

Guidance literature:: Multi-step reaction with 5 steps

1: 95 percent / p-toluenesulfonic acid / CH₂Cl₂ / 0.5 h

2: 79 percent / diisobutylaluminum hydride / toluene; hexane / 0.33 h

3: 1.) sodium methylsulfinylcarbanide / 1.) Me₂SO, 2.) Me₂SO, 6 h

4: Jones reagent / acetone / 0.08 h / -20 °C

5: 65percent aq. acetic acid / 14 h

With jones reagent; sodium methylsulfinylcarbanide; diisobutylaluminium hydride; toluene-4-sulfonic acid; acetic acid; In hexane; dichloromethane; acetone; toluene;
DOI:10.1021/jm00143a018

Reference yield:

: 286840-19-5
(3aR,4R,5R,6aS)-4-[(E)-(R)-4-Phenoxy-3-(tetrahydro-pyran-2-yloxy)-but-1-enyl]-5-(tetrahydro-pyran-2-yloxy)-hexahydro-cyclopenta[b]furan-2-ol

: 54382-74-0
16-phenoxy-ω-tetranor-PGE₂

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) sodium methylsulfinylcarbanide / 1.) Me₂SO, 2.) Me₂SO, 6 h

2: Jones reagent / acetone / 0.08 h / -20 °C

3: 65percent aq. acetic acid / 14 h

With jones reagent; sodium methylsulfinylcarbanide; acetic acid; In acetone;
DOI:10.1021/jm00143a018

Reference yield:

: 62989-31-5
(Z)-7-[(1R,2R,3R,5S)-5-Hydroxy-2-[(E)-(R)-4-phenoxy-3-(tetrahydro-pyran-2-yloxy)-but-1-enyl]-3-(tetrahydro-pyran-2-yloxy)-cyclopentyl]-hept-5-enoic acid

: 54382-74-0
16-phenoxy-ω-tetranor-PGE₂

Guidance literature:: Multi-step reaction with 2 steps

1: Jones reagent / acetone / 0.08 h / -20 °C

2: 65percent aq. acetic acid / 14 h

With jones reagent; acetic acid; In acetone;
DOI:10.1021/jm00143a018