51638-93-8 Usage
Uses
Used in Pharmaceutical Industry:
2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-, (3aR,4R,5R,6aS)is used as a pharmaceutical compound for its potential biological activities. The presence of hydroxyl and phenoxy groups may allow for interactions with biological targets, making it a candidate for drug development. Its complex structure and stereochemistry could be leveraged to design molecules with specific therapeutic effects.
Used in Organic Synthesis:
In the field of organic synthesis, 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-, (3aR,4R,5R,6aS)serves as a valuable intermediate or precursor. Its unique structure and functional groups can be utilized in the synthesis of other complex organic molecules, contributing to the development of novel chemical entities with various applications.
Used as a Precursor in Synthesis:
2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-, (3aR,4R,5R,6aS)is used as a precursor in the synthesis of other complex molecules. Its cyclopentane and furan rings, along with the hydrocarbon chain and functional groups, provide a versatile platform for further chemical modifications and the creation of new compounds with specific properties and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 51638-93-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,1,6,3 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 51638-93:
(7*5)+(6*1)+(5*6)+(4*3)+(3*8)+(2*9)+(1*3)=128
128 % 10 = 8
So 51638-93-8 is a valid CAS Registry Number.
51638-93-8Relevant academic research and scientific papers
PROSTANOIDS. XXIX. SELECTIVE OXIDATION OF 7α-HYDROXY-6β-HYDROXYMETHYLENE-2-OXABICYCLOOCTAN-3-ONE BISTRIMETHYLSILYL ETHER BY REAGENTS BASED ON CHROMIUM(VI) AS KEY STAGE IN SYNTHESIS OF SULPROSTONE
Tolstikov, G. A.,Adler, M. E.,Miftakhov, M. S.
, p. 1908 - 1914 (2007/10/02)
7α-Hydroxy-6β-(3-oxo-4-phenoxy-1E-butenyl)-2-oxabicyclooctan-3-one was synthesized by the selective oxidation of 7α-hydroxy-6β-hydroxymethylene-2-oxabicyclooctan-3-one bistrimethylsilyl ether with CrO3*2Py/SiO2 and subsequent condensation of the intermediate 7α-trimethylsiloxy-6β-formyl-2-oxabicyclooctan-3-one with dimethyl 2-oxo-3-phenoxypropylphosphonate.The product was then converted into the methanesulfonamide of 16-phenoxy-17,18,19,20-tetranorprostaglandin E2 (sulprostone).
N-(Methanesulfonyl)-16-phenoxyprostaglandincarboxamides: Tissue-Selective, Uterine Stimulants
Schaaf, Thomas K.,Bindra, Jasjit S.,Eggler, James F.,Plattner, Jacob J.,Nelson, A. James,et al.
, p. 1353 - 1359 (2007/10/02)
In an effort to develop tissue-selective prostaglandin analogues resistant to the metabolic inactivating pathways of the natural materials, hybrid compounds modified both at C-1 with a sulfonimide moiety and in the n-amylcarbinol side chain with substituted phenoxy groups were synthesized and evaluated in a variety of in vitro and in vivo models.Several of these analogues exhibited potent, tissue-selective, uterine stimulant activity, a finding subsequently confirmed in clinical studies with one member of this series, N-(methanesulfonyl)-16-phenoxy-ω-tetranor-PGE2-carboxamide (CP-34089/ZK-57671, sulprostone).
