5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol

Base Information

Chemical Name:5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol
CAS No.:936006-11-0
Molecular Formula:C₁₉H₁₈O₄
Molecular Weight:310.35
Hs Code.:2932999099
Mol file:936006-11-0.mol

Synonyms:5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol;5-(6-Hydroxy-2-benzofuranyl)-2-[(1E)-3-methyl-1-buten-1-yl]-1,3-benzenediol;Artoindonesianin B 1;5-(6-Hydroxybenzofuran-2-yl)-2-(3-Methylbut-1-en-1-yl)benzene-1,3-diol

Suppliers and Price of 5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(6-Hydroxybenzofuran-2-Yl)-2-(3-Methylbut-1-Enyl)benzene-1,3-Diol 95+%
5mg
$ 930.00

Arctom
5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol
5mg
$ 593.00

Total 10 raw suppliers

Chemical Property of 5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol

Chemical Property:

Melting Point:214-215 °C
Boiling Point:432.2±25.0 °C(Predicted)
PKA:8.91±0.45(Predicted)
PSA：73.83000
Density:1.286±0.06 g/cm3(Predicted)
LogP:4.88580

Purity/Quality:

97% ^*data from raw suppliers

5-(6-Hydroxybenzofuran-2-Yl)-2-(3-Methylbut-1-Enyl)benzene-1,3-Diol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol

There total 22 articles about 5-(6-Hydroxybenzofuran-2-yl)-2-(3-methylbut-1-enyl)benzene-1,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 2-[[3,5-dimethoxy-4-(3-methyl-1-butenyl)]phenyl]-6-hydroxybenzofuran

: 936006-11-0
2-[3',5'-dihydroxy-4'-(3-methlbut-1-enyl)phenyl]-6-hydroxybenzofuran

Guidance literature:: With n-butyllithium; diphenylphosphane; In tetrahydrofuran; hexane; for 36h; Inert atmosphere; Reflux;
DOI:10.1016/j.tetlet.2015.05.093

Reference yield:

: 6272-26-0
6-hydroxybenzofuran-3-one

: 936006-11-0
2-[3',5'-dihydroxy-4'-(3-methlbut-1-enyl)phenyl]-6-hydroxybenzofuran

Guidance literature:: Multi-step reaction with 5 steps

1.1: 1H-imidazole / tetrahydrofuran / 4 h / 0 - 20 °C

2.1: sodium tetrahydroborate / methanol / 4 h / 20 °C

3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C

3.2: -78 - 20 °C

3.3: 20 °C / pH 5

4.1: 1H-imidazole / tetrahydrofuran / 2 h / 20 °C

5.1: n-butyllithium; diphenylphosphane / tetrahydrofuran; hexane / 36 h / Inert atmosphere; Reflux

With 1H-imidazole; sodium tetrahydroborate; n-butyllithium; diphenylphosphane; In tetrahydrofuran; methanol; hexane;
DOI:10.1016/j.tetlet.2015.05.093

Reference yield:

: C₁₁H₁₂O₃

: 936006-11-0
2-[3',5'-dihydroxy-4'-(3-methlbut-1-enyl)phenyl]-6-hydroxybenzofuran

Guidance literature:: Multi-step reaction with 8 steps

1: potassium carbonate / N,N-dimethyl-formamide / 12 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 2 h / 0 - 50 °C

3: sodium hydroxide / water; 1,4-dioxane / 1 h / 80 °C

4: Pd(PPh₃)₂Cl₂; copper(l) iodide; triethylamine / N,N-dimethyl-formamide / 24 h / 20 °C

5: ruthenium trichloride; sodium periodate; benzyltriethylammonium chloride / ethyl acetate / 2 h / 20 °C

6: tetrahydrofuran / 0 °C

7: toluene-4-sulfonic acid / toluene / Reflux

8: lithium diphenylphosphide / tetrahydrofuran / Reflux

With ruthenium trichloride; sodium periodate; copper(l) iodide; Pd(PPh₃)₂Cl₂; potassium carbonate; toluene-4-sulfonic acid; benzyltriethylammonium chloride; triethylamine; lithium diphenylphosphide; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; water; ethyl acetate; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.tetlet.2015.05.093