N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-1-cyclohexylmethanesulfonamide

Base Information

Chemical Name:N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-1-cyclohexylmethanesulfonamide
CAS No.:740873-05-6
Molecular Formula:C₂₁H₃₆N₄O₂S
Molecular Weight:408.608
Hs Code.:

Synonyms:N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-1-cyclohexylmethanesulfonamide

Suppliers and Price of N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-1-cyclohexylmethanesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-1-cyclohexylmethanesulfonamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-1-cyclohexylmethanesulfonamide

There total 5 articles about N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-1-cyclohexylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 740873-04-5
C-cyclohexyl-N-{4-[4-(3-nitrophenyl)piperazin-1-yl]butyl}methanesulfonamide

: 740873-05-6
N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-C-cyclohexylmethanesulfonamide

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In methanol; at -10 - 20 ℃;
DOI:10.1021/jm0508641

Reference yield:

: 54054-85-2
1-(3-nitrophenyl)piperazine

: 740873-05-6
N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-C-cyclohexylmethanesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: 63 percent / Et₃N / tetrahydrofuran / 48 h / 20 °C

2: CH₂Cl₂ / 2 h / 0 °C

3: 88 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

4: 76 percent / SnCl₂; aq. HCl / methanol / -10 - 20 °C

With hydrogenchloride; triethylamine; tin(ll) chloride; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm0508641

Reference yield:

: 740873-01-2
{4-[4-(3-nitrophenyl)piperazin-1-yl]butyl}carbamic acid tert-butyl ester

: 740873-05-6
N-{4-[4-(3-aminophenyl)piperazin-1-yl]butyl}-C-cyclohexylmethanesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: CH₂Cl₂ / 2 h / 0 °C

2: 88 percent / Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

3: 76 percent / SnCl₂; aq. HCl / methanol / -10 - 20 °C

With hydrogenchloride; triethylamine; tin(ll) chloride; In methanol; dichloromethane;
DOI:10.1021/jm0508641