3α-Acetyloxy-5α-pregnan-20-one

Base Information

Chemical Name:3α-Acetyloxy-5α-pregnan-20-one
CAS No.:1491-77-6
Molecular Formula:C23H36O3
Molecular Weight:360.537
Hs Code.:
Mol file:1491-77-6.mol

Synonyms:3α-Acetyloxy-5α-pregnan-20-one;(3α,5β)-3-(Acetyloxy)pregnan-20-one

Suppliers and Price of 3α-Acetyloxy-5α-pregnan-20-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
(3α,5β)-3-(Acetyloxy)pregnan-20-one
100 mg
$ 875.00

Total 5 raw suppliers

Chemical Property of 3α-Acetyloxy-5α-pregnan-20-one

Chemical Property:

PSA：43.37000
LogP:5.16600

Purity/Quality:

99% ^*data from raw suppliers

(3α,5β)-3-(Acetyloxy)pregnan-20-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3α-Acetyloxy-5α-pregnan-20-one

There total 21 articles about 3α-Acetyloxy-5α-pregnan-20-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 128-20-1,128-21-2,516-54-1,516-55-2,4243-94-1,4320-08-5,4406-35-3,4406-37-5,4469-03-8,13089-85-5,13089-86-6,14615-01-1,21788-58-9,24557-99-1,25126-79-8,26961-00-2,36027-63-1,39845-99-3,40135-22-6,72691-57-7,81076-02-0,95118-68-6,110350-90-8
3β-hydroxy-(5ξ)-pregnan-20-one

: 108-24-7
acetic anhydride

: 906-83-2,1491-77-6,2394-44-7,6003-24-3,10002-82-1,23097-04-3,33999-95-0,34000-02-7,40129-07-5,65556-92-5,95720-67-5,95720-68-6,95720-69-7,96611-81-3,102679-41-4,106760-08-1
Pregnanolon-3β-acetat

Guidance literature:: With pyridine; In pyridine; at 20 ℃; for 2h;

Reference yield:

: 128-20-1,128-21-2,516-54-1,516-55-2,4243-94-1,4320-08-5,4406-35-3,4406-37-5,4469-03-8,13089-85-5,13089-86-6,14615-01-1,21788-58-9,24557-99-1,25126-79-8,26961-00-2,36027-63-1,39845-99-3,40135-22-6,72691-57-7,81076-02-0,95118-68-6,110350-90-8
PREGNANOLONE

: 108-24-7
acetic anhydride

: 1491-77-6
3α-acetoxy-5β-pregnan-20-one

Guidance literature:: DOI:10.1021/ja01286a062

Reference yield:

: 4057-84-5
acetyllithocholic acid

: 1491-77-6
3α-acetoxy-5β-pregnan-20-one

Guidance literature:: Multi-step reaction with 4 steps

1: 63 percent / Pb(OAc)4, Cu(OAc)2, pyridine / benzene / 4 h / Heating

2: 90 percent / Li/ethylenediamine / 0.25 h / Heating

3: pyridine / 18 h / Ambient temperature

4: 1.) O₃, 2.) Jones reagent / 1.) CH₂Cl₂, -10 deg C, 2.) acetone, 0 deg C

With pyridine; lead(IV) acetate; jones reagent; copper diacetate; lithium; ozone; ethylenediamine; In benzene;
DOI:10.1515/znb-1984-1125