2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde

Base Information

Chemical Name:2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde
CAS No.:96649-00-2
Molecular Formula:C₁₂H₁₅NO₂
Molecular Weight:205.257
Hs Code.:2933990090
DSSTox Substance ID:DTXSID701332211
ChEMBL ID:CHEMBL1570343
Mol file:96649-00-2.mol

Synonyms:2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde;96649-00-2;2-methoxy-4-(pyrrolidin-1-yl)benzaldehyde;2-methoxy-4-pyrrolidin-1-ylbenzaldehyde;2-methoxy-4-(1-pyrrolidinyl)benzaldehyde;MLS000709614;CHEMBL1570343;SCHEMBL23636917;DTXSID701332211;HMS2733J22;STL388404;AKOS000102036;SMR000288081;BB 0262388;FT-0747144

Suppliers and Price of 2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde
1g
$ 650.00

Matrix Scientific
2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde
500mg
$ 423.00

Crysdot
2-Methoxy-4-(pyrrolidin-1-yl)benzaldehyde 97%
1g
$ 307.00

American Custom Chemicals Corporation
2-METHOXY-4-PYRROLIDIN-1-YL-BENZALDEHYDE 95.00%
500MG
$ 777.32

AK Scientific
2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde
1g
$ 927.00

Total 6 raw suppliers

Chemical Property of 2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde

Chemical Property:

PSA：29.54000
LogP:2.17290
XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:205.110278721
Heavy Atom Count:15
Complexity:214

Purity/Quality:

97% ^*data from raw suppliers

2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)N2CCCC2)C=O

Technology Process of 2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde

There total 3 articles about 2-Methoxy-4-pyrrolidin-1-yl-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 90-04-0
2-methoxy-phenylamine

: 96649-00-2
2-methoxy-4-(1-pyrrolidinyl)benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; sodium stearate; tetrabutylammomium bromide / water; ethanol / 100 °C

2: trichlorophosphate / 0 - 80 °C

With tetrabutylammomium bromide; sodium stearate; potassium carbonate; trichlorophosphate; In ethanol; water; 2: |Vilsmeier-Haack Formylation / 2: |Vilsmeier-Haack Formylation;
DOI:10.1021/acsmedchemlett.5b00049

Reference yield:

: 32040-07-6
1-(3-methoxyphenyl)pyrrolidine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 96649-00-2
2-methoxy-4-(1-pyrrolidinyl)benzaldehyde

Guidance literature:: 1-(3-methoxyphenyl)pyrrolidine; N,N-dimethyl-formamide; With trichlorophosphate; at 0 - 80 ℃;

With sodium carbonate;
DOI:10.1021/acsmedchemlett.5b00049

Reference yield:

: 32040-07-6
1-(3-methoxyphenyl)pyrrolidine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 96648-99-6
2-methoxy-6-(pyrrolidin-1-yl)benzaldehyde

: 96649-00-2
2-methoxy-4-(1-pyrrolidinyl)benzaldehyde

Guidance literature:: With n-butyllithium; Product distribution; other 3-(dialkylamino)phenols O-protected, other solvents, other time, other electrophiles;
DOI:10.1021/jo00215a020