tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate

Base Information

• Chemical Name: tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate
• CAS No.: 73470-46-9
• Molecular Formula: C9H18N2O3
• Molecular Weight: 202.254
• Hs Code.: 2924199090
• Mol file: 73470-46-9.mol

Synonyms:tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate

Chemical Property of tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate

Chemical Property:

• PSA: 85.90000
• LogP: 2.12910
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl(1-amino-2-methyl-1-oxopropan-2-yl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate

There total 7 articles about tert-Butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

Boc-Aib-OH (30992-29-1) → tert-butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate (73470-46-9)

Guidance literature:

Boc-Aib-OH; With pyridine; di-tert-butyl dicarbonate; In acetonitrile; at 20 ℃; for 0.333333h;

With ammonia; In water; acetonitrile; for 4.33333h;

Reference yield: 57.6%

→ tert-butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate (73470-46-9)

Guidance literature:

Reference yield: 31.0%

Boc-Aib-O-COO-isoBu → tert-butyl (1-amino-2-methyl-1-oxopropan-2-yl)carbamate (73470-46-9)

Guidance literature:

With ammonia; In water; at -20 - 25 ℃;

upstream raw materials:

Boc-Aib-OH

di-tert-butyl dicarbonate

Downstream raw materials:

2-Amino-2-methyl-propionamide hydrochloride

1,1-dimethylethyl {1-[5-(2-chloro-4-pyrimidinyl)-4-(3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-2-yl]-1-methylethyl}carbamate

1,1-dimethylethyl [1-(5-(2-chloro-4-pyrimidinyl)-4-{2-fluoro-3-[(3-furanylsulfonyl)amino]phenyl}-1,3-thiazol-2-yl)-1-methylethyl]carbamate

1,1-dimethylethyl {1-[4-(3-amino-2-fluorophenyl)-5-(2-chloro-4-pyrimidinyl)-1,3-thiazol-2-yl]-1-methylethyl}carbamate