sodium 2-[[3-(trifluoromethyl)phenyl]amino]benzoate

Base Information

• Chemical Name: sodium 2-[[3-(trifluoromethyl)phenyl]amino]benzoate
• CAS No.: 1977-00-0
• Molecular Formula: C14H10 F3 N O2 . Na
• Molecular Weight: 303.216
• Hs Code.: 2922499990
• Mol file: 1977-00-0.mol

Synonyms:Anthranilicacid, N-(a,a,a-trifluoro-m-tolyl)-, monosodium salt (8CI); Benzoic acid,2-[[3-(trifluoromethyl)phenyl]amino]-, monosodium salt (9CI); Flufenamic acidsodium salt; Sodium 2-[m-(trifluoromethyl)anilino]benzoate; SodiumN-[3-(trifluoromethyl)phenyl]anthranilate; Sodium flufenamate

Chemical Property of sodium 2-[[3-(trifluoromethyl)phenyl]amino]benzoate

Chemical Property:

• Vapor Pressure: 2.97E-06mmHg at 25°C
• Boiling Point: 373.9°Cat760mmHg
• Flash Point: 179.9°C
• PSA: 52.16000
• Density: g/cm³
• LogP: 2.88550

Purity/Quality:

99% ^*data from raw suppliers

Sodium2-[[3-(Trifluoromethyl)phenyl]amino]benzoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of sodium 2-[[3-(trifluoromethyl)phenyl]amino]benzoate

There total 1 articles about sodium 2-[[3-(trifluoromethyl)phenyl]amino]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

flufenamic acid (530-78-9) → sodium salt of {N-(α,α,α-trifluoro-m-tolyl)anthranilic acid} (1977-00-0)

Guidance literature:

With sodium hydroxide;

DOI:10.1134/S0036024415060023

Reference yield: 92.0%

sodium salt of {N-(α,α,α-trifluoro-m-tolyl)anthranilic acid} (1977-00-0) + dimethylchloromethylphosphine oxide (1638-75-1) → dimethylphosphinyl-methyl N-(3-trifluoromethylphenyl)-anthranilate (61148-97-8)

Guidance literature:

In N,N-dimethyl-formamide; at 150 ℃;

Reference yield: 65.0%

N-(chloromethyloxycarbonyl)glycine diethylamide (934548-23-9) + sodium salt of {N-(α,α,α-trifluoro-m-tolyl)anthranilic acid} (1977-00-0) → 2-(3-trifluoromethyl-phenylamino)-benzoic acid diethylcarbamoylmethylcarbamoyloxymethyl ester

Guidance literature:

With tetrabutylammomium bromide; triethylamine; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1002/ardp.200600145

upstream raw materials:

flufenamic acid

Downstream raw materials:

dimethylphosphinyl-propyl N-(3-trifluoromethylphenyl)-anthranilate

dimethylphosphinyl-methyl N-(3-trifluoromethylphenyl)-anthranilate

flufenamic acid