2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione

Base Information Edit

Chemical Name:2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
CAS No.:19171-18-7
Molecular Formula:C13H9N3O6
Molecular Weight:303.231
Hs Code.:2925190090
European Community (EC) Number:807-865-0
UNII:OH13HKS17A
DSSTox Substance ID:DTXSID00940816
Nikkaji Number:J107.153J
Wikidata:Q27894262
ChEMBL ID:CHEMBL370441
Mol file:19171-18-7.mol

Synonyms:19171-18-7;2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione;4-Nitrothalidomide;3-Nitrothalidomide;1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-nitro-;2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindole-1,3-dione;N-(2,6-Dioxo-3-piperidyl)-3-nitrophthalimide;Phthalimide, N-(2,6-dioxo-3-piperidyl)-3-nitro-;OH13HKS17A;CHEMBL370441;3-(1',3'-Dioxo-4'-nitroisoindolinyl-2')-2,6-dioxopiperidine;2-(2,6-Dioxo-3-piperidinyl)-4-nitro-1H-isoindole-1,3(2H)-dione;2-(2,6-dioxopiperidin-3-yl)-4-nitro-1H-isoindole-1,3(2H)-dione;Nitrothalidomide;UNII-OH13HKS17A;SCHEMBL1398974;C13H9N2O6;DTXSID00940816;AMY38937;BCP10969;CS-M1140;BDBM50516600;C13-H9-N2-O6;MFCD01748356;4-NITROTHALIDOMIDE, (+/-)-;DS-5838;SB66228;LS-109466;FT-0733033;O10454;EN300-6732712;A880361;Q27894262;1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-nitro-isoindole;2-(2,6-DIOXOPIPERIDIN-3-YL)-4-NITRO-ISOINDOLE-1,3-DIONE;2-(2,6-dioxopiperidin-3-yl)-4-nitro-2,3-dihydro-1H-isoindole-1,3-dione;2-(6-Hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-4-nitro-1H-isoindole-1,3(2H)-dione

Suppliers and Price of 2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Nitrothalidomide
5mg
$ 65.00

Crysdot
2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione 95+%
250mg
$ 246.00

Crysdot
2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione 95+%
1g
$ 614.00

ChemScene
2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
500mg
$ 528.00

Chemenu
2-(2,6-dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione 95%+
10g
$ 276.00

Biosynth Carbosynth
2-(2,6Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
25 mg
$ 125.00

Biosynth Carbosynth
2-(2,6Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
250 mg
$ 450.00

Biosynth Carbosynth
2-(2,6Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
100 mg
$ 310.00

Biosynth Carbosynth
2-(2,6Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
50 mg
$ 200.00

Biosynth Carbosynth
2-(2,6Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione
10 mg
$ 60.00

Total 70 raw suppliers

Chemical Property of 2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione Edit

Chemical Property:

Vapor Pressure:1.63E-14mmHg at 25°C
Melting Point:>200°C (dec.)
Boiling Point:603.4°Cat760mmHg
PKA:10.55±0.40(Predicted)
Flash Point:318.7°C
PSA：132.86000
Density:1.651g/cm³
LogP:0.73300
Storage Temp.:Inert atmosphere,Room Temperature
Solubility.:Acetonitrile (Slightly, Heated, Sonicated), DMSO (Slightly)
XLogP3:0.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:303.04913502
Heavy Atom Count:22
Complexity:583

Purity/Quality:

97% ^*data from raw suppliers

4-Nitrothalidomide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)[N+](=O)[O-]
Uses 4-Nitrothalidomide is a compound involved in the preparation of Pomalidomide (P688200), a thalidomide derivative and potent inhibitor of TNF-α production.

Technology Process of 2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione

There total 27 articles about 2-(2,6-Dioxopiperidin-3-yl)-4-nitroisoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%