Ethanone, 2-chloro-2,2-difluoro-1-(4-methoxyphenyl)- (9CI)

Base Information

Chemical Name:Ethanone, 2-chloro-2,2-difluoro-1-(4-methoxyphenyl)- (9CI)
CAS No.:173067-08-8
Molecular Formula:C9H7ClF2O2
Molecular Weight:220.6004864
Hs Code.:
Mol file:173067-08-8.mol

Synonyms:Ethanone, 2-chloro-2,2-difluoro-1-(4-methoxyphenyl)- (9CI)

Suppliers and Price of Ethanone, 2-chloro-2,2-difluoro-1-(4-methoxyphenyl)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Rieke Metals
2-Chloro-2,2-difluoro-1-(4-methoxy-phenyl)-ethanone
5g
$ 1728.00

Rieke Metals
2-Chloro-2,2-difluoro-1-(4-methoxy-phenyl)-ethanone
1g
$ 661.00

Total 2 raw suppliers

Chemical Property of Ethanone, 2-chloro-2,2-difluoro-1-(4-methoxyphenyl)- (9CI)

Chemical Property:

PSA：26.30000
LogP:2.70950

Purity/Quality:

99%+ ^*data from raw suppliers

2-Chloro-2,2-difluoro-1-(4-methoxy-phenyl)-ethanone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Ethanone, 2-chloro-2,2-difluoro-1-(4-methoxyphenyl)- (9CI)

There total 1 articles about Ethanone, 2-chloro-2,2-difluoro-1-(4-methoxyphenyl)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104-92-7
1-bromo-4-methoxy-benzene

: 383-62-0
ethyl 2-chloro-2,2-difluoroacetate

: 173067-08-8
chlorodifluoromethyl p-methoxyphenyl ketone

Guidance literature:: With magnesium; Yield given. Multistep reaction; 1.) THF, 2.) THF, -78 deg C, 1 h;
DOI:10.1016/0040-4020(95)00785-7

Reference yield: 98.0%

: 173067-08-8
chlorodifluoromethyl p-methoxyphenyl ketone

: 173067-09-9
2-chloro-2,2-difluoro-1-(4-methoxyphenyl)ethan-1-ol

Guidance literature:: With sodium tetrahydroborate; In ethanol;
DOI:10.1016/0040-4020(95)00785-7

Reference yield:

: 173067-08-8
chlorodifluoromethyl p-methoxyphenyl ketone

: 2,2-difluoro-3-methoxy-1-p-methoxyphenyl-3-phenyl-1-propanone

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / NaBH₄ / ethanol

2: 98 percent / NaH / tetrahydrofuran / Ambient temperature

3: 1.) diisopropylamine, butyllithium / 1.) hexane/THF, -78 deg C, 2.) hexane/THF, -78 deg C, 6 h

4: 95 percent / SbCl₆*N(4-bromophenyl)3 / CH₂Cl₂ / 1 h / 0 °C

With sodium tetrahydroborate; n-butyllithium; sodium hydride; tris(p-bromophenylammoniumyl) hexachloroantimonate; diisopropylamine; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1016/0040-4020(95)00785-7