383-62-0 Usage
Description
Chlorodifluoroacetic acid ethyl ester, also known as Ethyl chlorodifluoroacetate (ECDFA), is a clear colorless liquid with unique chemical properties. It is a compound that undergoes Reformatskii reaction with various aldehydes in DMF and reacts with phenylacetylene to produce ethyl α,α-difluoro-4-phenyl-3-butenoates.
Uses
Used in Chemical Synthesis:
Chlorodifluoroacetic acid ethyl ester is used as a starting reagent for the synthesis of 3-gem-difluoro-2-ethoxy allylic alcohols. Its unique chemical properties make it a valuable component in the creation of various chemical compounds and intermediates.
Used in Pharmaceutical Industry:
Chlorodifluoroacetic acid ethyl ester is used as a key intermediate in the synthesis of certain pharmaceutical compounds. Its ability to undergo specific chemical reactions allows for the development of new drugs and medications.
Used in Research and Development:
In the field of research and development, Chlorodifluoroacetic acid ethyl ester is utilized for studying its chemical properties and potential applications in various industries. Its unique reactivity with other compounds opens up new avenues for scientific exploration and innovation.
Used in Specialty Chemicals:
Chlorodifluoroacetic acid ethyl ester is employed in the production of specialty chemicals, where its specific properties are harnessed to create unique products with tailored characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 383-62-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 3 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 383-62:
(5*3)+(4*8)+(3*3)+(2*6)+(1*2)=70
70 % 10 = 0
So 383-62-0 is a valid CAS Registry Number.
InChI:InChI=1/C4H5ClF2O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3
383-62-0Relevant articles and documents
METHOD FOR PRODUCING DIFLUORO-ACETYL-ACETIC ACID ALKYLESTERS
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Page 13, (2008/06/13)
The invention relates to a three-stage method for producing 4, 4-difluoro-acetyl-acetic acid alkylesters. In a first stage, a reaction of 4-chloro-4, 4-difluoro-acetyl-acetic acid alkylesters with trialkyl-phosphites of formula (III) P(OR1)3 is carried out, wherein R1 is C1-C4 alkyl, the R1 groups can be identical or different for producing alkyl-phosphonic acid esters of formula (IV) which react with amine of formula (V) during a second stage, wherein R2 and R3 are hydrogen or C1-C4 alkyl independent of each other, or jointly CH2-CH2-O-CH2-CH2- for forming enamines of formula (VI), wherein R2 and R3 have already mentioned significance, said enamines being hydrolysed in the presence of an acid during a third stage.
Process for the preparation of alkyl halodifluoroacetates
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, (2008/06/13)
For the preparation of alkyl halodifluoroacetates, a 1,1-difluorotetrahaloethane is reacted with an alcohol in the presence of air and/or oxygen and a free-radical initiator, such as for example an azo compound, e.g., azobis(isobutyronitrile).
