CIS-ETHYL 2-FLUOROCYCLOPROPANECARBOXYLATE

Base Information

• Chemical Name: CIS-ETHYL 2-FLUOROCYCLOPROPANECARBOXYLATE
• CAS No.: 84388-71-6
• Molecular Formula: C₆H₉FO₂
• Molecular Weight: 132.135
• Hs Code.: 2916209090
• Mol file: 84388-71-6.mol

Synonyms:CIS-ETHYL 2-FLUOROCYCLOPROPANECARBOXYLATE

Chemical Property of CIS-ETHYL 2-FLUOROCYCLOPROPANECARBOXYLATE

Chemical Property:

• PSA: 26.30000
• LogP: 0.90750

Purity/Quality:

99.5% ^*data from raw suppliers

(cis)-Ethyl 2-fluorocyclopropanecarboxylate ^*data from reagent suppliers

Safty Information:

• Statements: 10-36/37/38
• Safety Statements: 16-36/37/39-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CIS-ETHYL 2-FLUOROCYCLOPROPANECARBOXYLATE

There total 10 articles about CIS-ETHYL 2-FLUOROCYCLOPROPANECARBOXYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.3%

ethanol (64-17-5) + (±)-cis-2-fluorocyclopropanecarboxylic acid (167073-07-6,167073-08-7) → cis-ethyl 2-fluorocyclopropanecarboxylate (188428-48-0,84388-71-6)

Guidance literature:

With sulfuric acid; for 8h; Heating;

DOI:10.1016/S0957-4166(98)00321-8

Reference yield: 88.9%

2-chloro-2-fluorocyclopropanecarboxylic acid ethyl ester (155051-93-7) + ethylenediamine (107-15-3,85404-18-8) → ethyl trans-2-fluorocyclopropanecarboxylate (188428-48-0,84388-71-6)

Guidance literature:

aluminum nickel; In ethanol;

Reference yield: 81.0%

ethyl 1-chloro-2-fluoro-cyclopropane-1-carboxylate + ethylenediamine (107-15-3,85404-18-8) → ethyl trans-2-fluorocyclopropanecarboxylate (188428-48-0,84388-71-6)

Guidance literature:

aluminum nickel; In ethanol;

upstream raw materials:

ethanol

(±)-cis-2-fluorocyclopropanecarboxylic acid

2-chloro-2-fluorocyclopropanecarboxylic acid ethyl ester

cis-ethyl 2-fluorocyclopropanecarboxylate

Refernces

• 1、 -. "PROCESS FOR PRODUCING 1,2-CIS-2-FLUOROCYCLOPROPANE-1-CARBOXYLIC ESTER COMPOUND". Page/Page column 10-11. . Retrieved 2008/06/13.
• 2、 -. "Process for producing 2-fluorine-1-cyclopropane carboxylic acid derivatives by reductive dehalogenation". . . Retrieved 2008/06/13.