BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-

Base Information

• Chemical Name: BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-
• CAS No.: 364355-93-1
• Molecular Formula: C24H20Cl2FN5O3S
• Molecular Weight: 548
• Mol file: 364355-93-1.mol

Synonyms:BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-;N1-[4-[4-Amino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-fluorophenyl]-2,3-dichloro-1-benzenesulfonamide

Chemical Property of BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-

Chemical Property:

• PSA: 128.35000
• Density: 1.62
• LogP: 7.34640

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro-

There total 1 articles about BenzenesulfonaMide, N-[4-[4-aMino-7-(4-oxocyclohexyl)-7H-pyrrolo[2,3-d]pyriMidin-5-yl]-2-fluorophenyl]-2,3-dichloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[4-amino-5-(4-amino-3-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-1-cyclohexanone (364355-99-7) + dichlorobenzenesulfonyl chloride (82417-45-6) → N1-(4-{4-amino-7-(4-oxo-cyclohexyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-fluorophenyl)-2,3-dichloro-1-benzenesulfonamide (364355-93-1)

Guidance literature:

In pyridine; dichloromethane;

Reference yield:

1-methyl-piperazine (109-01-3) + N1-(4-{4-amino-7-(4-oxo-cyclohexyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-fluorophenyl)-2,3-dichloro-1-benzenesulfonamide (364355-93-1) → trans-N1-(4-{4-amino-7-[4-(4-methylpiperazino)cyclohexyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-fluorophenyl)-2,3-dichloro-1-benzenesulfonamide

Guidance literature:

With sodium tris(acetoxy)borohydride; In acetic acid; 1,2-dichloro-ethane;

upstream raw materials:

4-[4-amino-5-(4-amino-3-chlorophenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl]-1-cyclohexanone

dichlorobenzenesulfonyl chloride

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