4-(2-(tert-butyldiMethylsilyloxy)ethyl)-1-trityl-1H-iMidazole

Base Information

Chemical Name:4-(2-(tert-butyldiMethylsilyloxy)ethyl)-1-trityl-1H-iMidazole
CAS No.:928136-82-7
Molecular Formula:C30H36N2OSi
Molecular Weight:468.714
Hs Code.:
Mol file:928136-82-7.mol

Synonyms:4-(2-(tert-butyldiMethylsilyloxy)ethyl)-1-trityl-1H-iMidazole

Suppliers and Price of 4-(2-(tert-butyldiMethylsilyloxy)ethyl)-1-trityl-1H-iMidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-1-trityl-1H-imidazole 95+%
1g
$ 518.00

Chemenu
4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-1-trityl-1H-imidazole 95%
1g
$ 489.00

Alichem
4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-1-trityl-1H-imidazole
1g
$ 447.32

Total 5 raw suppliers

Chemical Property of 4-(2-(tert-butyldiMethylsilyloxy)ethyl)-1-trityl-1H-iMidazole

Chemical Property:

Boiling Point:544.6±38.0 °C (760 mmHg)
PSA：27.05000
Density:1.00±0.1 g/cm3 (20 °C, 760 mmHg)
LogP:7.28760

Purity/Quality:

97% ^*data from raw suppliers

4-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-1-trityl-1H-imidazole 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(2-(tert-butyldiMethylsilyloxy)ethyl)-1-trityl-1H-iMidazole

There total 4 articles about 4-(2-(tert-butyldiMethylsilyloxy)ethyl)-1-trityl-1H-iMidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 127607-62-9
1-triphenylmethyl-4-(2-hydroxyethyl)-1H-imidazole

: 928136-82-7
4-[2-[(tert-butyldimethylsilyl)oxy]ethyl]-1-(triphenylmethyl)-1H-imidazole

Guidance literature:: With 1H-imidazole; In dichloromethane; at 25 ℃;

Reference yield:

: 76-83-5
trityl chloride

: 928136-82-7
4-[2-[(tert-butyldimethylsilyl)oxy]ethyl]-1-(triphenylmethyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyridine; methanol / 17 h / 20 °C

2.1: borane-THF / tetrahydrofuran / 0.5 h / 0 - 20 °C

2.2: 2 h / 90 °C

3.1: 1H-imidazole / dichloromethane / 20 °C

With 1H-imidazole; borane-THF; In tetrahydrofuran; pyridine; methanol; dichloromethane;
DOI:10.1021/ml400324c

Reference yield:

: 168632-03-9
1-triphenylmethyl-4-imidazolyl-acetic acid

: 928136-82-7
4-[2-[(tert-butyldimethylsilyl)oxy]ethyl]-1-(triphenylmethyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: borane-THF / tetrahydrofuran / 0.5 h / 0 - 20 °C

1.2: 2 h / 90 °C

2.1: 1H-imidazole / dichloromethane / 20 °C

With 1H-imidazole; borane-THF; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ml400324c