N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N'-Cyclohexylurea

Base Information

• Chemical Name: N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N'-Cyclohexylurea
• CAS No.: 10079-35-3
• Molecular Formula: C22H34N4O4S
• Molecular Weight: 450.59476
• Mol file: 10079-35-3.mol

Synonyms:N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N'-Cyclohexylurea;1-Cyclohexyl-3-[p-[(cyclohexylcarbaMoyl)sulfaMoyl] phenethyl]urea;N-[(CyclohexylaMino)carbonyl]-4-[2-[[(cyclohexylaMino)carbonyl]aMino]ethyl]- benzenesulfonaMide;N-[p-(β-Cyclohexylureidoe;GlibenclaMide (Glyburide) IMpurity C;Glipizide EP Impurity I

Chemical Property of N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N'-Cyclohexylurea

Chemical Property:

• Melting Point: 195-197℃
• PSA: 131.76000
• LogP: 5.45300
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl]N’-Cyclohexylurea ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Glipizide (G410225) impurity. N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N’-Cyclohexylurea (Glipizide EP Impurity I) is a Glipizide (G410225) impurity.

Technology Process of N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N'-Cyclohexylurea

There total 2 articles about N-[4-(β-Cyclohexylureidoethyl)benzensulfonyl] N'-Cyclohexylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide (10080-05-4) + Cyclohexyl isocyanate (3173-53-3) → C22H34N4O4S (10079-35-3)

Guidance literature:

4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide; With sodium hydroxide; In acetone; at 20 ℃; for 0.166667h;

Cyclohexyl isocyanate; In acetone; at 60 ℃; for 8h; Solvent; Reagent/catalyst;

Reference yield:

→ C22H34N4O4S (10079-35-3)

Guidance literature:

upstream raw materials:

4-[2-(3-Cyclohexyl-ureido)-ethyl]-benzenesulfonamide

Cyclohexyl isocyanate