Sedridine

Base Information

Chemical Name:Sedridine
CAS No.:501-83-7
Molecular Formula:C8H17NO
Molecular Weight:143.229
Hs Code.:2933399090
Mol file:501-83-7.mol

Synonyms:Sedridine;

Suppliers and Price of Sedridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Sedridine

Chemical Property:

Vapor Pressure:0.0052mmHg at 25°C
Melting Point:72-3°C
Boiling Point:244.1°Cat760mmHg
Flash Point:97.9°C
PSA：32.26000
Density:0.927g/cm³
LogP:1.22820

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description A further piperidine type alkaloid present in Sedum acre L., this base is dextrorotatory with [α]D + 17.1 ° (c 1. 23, EtOH). The phenylisocyanate derivative has been prepared as colourless crystals, m.p. 118-9°C. The structure has been established as (+ )-I-(2-piperidyl)-2-propanol.

Technology Process of Sedridine

There total 46 articles about Sedridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 14199-09-8
benzyl 2-(2-hydroxypropyl)piperidine-1-carboxylate

: 501-83-7,5320-51-4,10047-06-0,26171-47-1,26619-80-7,26619-87-4,26623-96-1
(+/-) Sedridine

: 501-83-7,5320-51-4,10047-06-0,26171-47-1,26619-80-7,26619-87-4,26623-96-1
(+/-) allosedridine

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethyl acetate; at 30 ℃; for 4h;
DOI:10.1016/j.tetlet.2015.03.001

Reference yield: 98.0%

: 14199-09-8
benzyl 2-(2-hydroxypropyl)piperidine-1-carboxylate

: 501-83-7,5320-51-4,10047-06-0,26171-47-1,26619-80-7,26619-87-4,26623-96-1
(+/-) Sedridine

: 501-83-7,5320-51-4,10047-06-0,26171-47-1,26619-80-7,26619-87-4,26623-96-1
(+/-) allosedridine

Guidance literature:: With palladium on activated charcoal; hydrogen; In ethyl acetate; at 30 ℃; for 4h;
DOI:10.1016/j.tetlet.2015.03.001

Reference yield:

: 87905-98-4
5-<(benzyloxycarbonyl)amino>pentanol

: 501-83-7
(+)-sedridine

Guidance literature:: Multi-step reaction with 5 steps

1.1: oxalyl dichloride / dimethyl sulfoxide; dichloromethane / 0.17 h / -78 °C / Inert atmosphere

1.2: 0.5 h / 20 °C / Inert atmosphere

2.1: toluene / 20 °C

3.1: (S)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine; trifluoroacetic acid / tetrahydrofuran / 20 °C

4.1: sodium tetrahydroborate; methanol / 20 °C

5.1: palladium(II) hydroxide; hydrogen / methanol

With methanol; (S)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanamine; sodium tetrahydroborate; oxalyl dichloride; hydrogen; palladium(II) hydroxide; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1002/ejoc.201900477