5-Aminopentan-1-ol

Base Information

• Chemical Name: 5-Aminopentan-1-ol
• CAS No.: 2508-29-4
• Molecular Formula: C5H13NO
• Molecular Weight: 103.164
• Hs Code.: 29221980
• European Community (EC) Number: 219-718-2
• DSSTox Substance ID: DTXSID10179771
• Nikkaji Number: J47.665J
• Wikidata: Q2817100
• ChEMBL ID: CHEMBL333552
• Mol file: 2508-29-4.mol

Synonyms:5-Amino-1-pentanol;5-Aminopentan-1-ol;2508-29-4;1-Pentanol, 5-amino-;5-aminopentanol;EINECS 219-718-2;Pentanol, 5-amino-;5-Amino-pentan-1-ol;MFCD00008237;5-AMINO-1-PENTANOL, 50% in Water;5-amino pentanol;5-amino-l-pentanol;5-Aminopentanol-1;5-hydroxypentylamine;1-amino-5-pentanol;5-amino-1 pentanol;1-amino-5-hydroxypentane;Tolmetin ?-D-Glucuronide;SCHEMBL2435;5-Amino-1-pentanol, 95%;CHEMBL333552;LQGKDMHENBFVRC-UHFFFAOYSA-;DTXSID10179771;STR06990;STL268891;AKOS009156388;CS-W013687;BP-13458;BP-25478;BP-30165;SY049614;A0875;FT-0619963;EN300-90243;I11482;Q2817100;W-109796;WHX

Chemical Property of 5-Aminopentan-1-ol

Chemical Property:

• Appearance/Colour: clear colourless liquid
• Vapor Pressure: 0.0208mmHg at 25°C
• Melting Point: 33-35 °C(lit.)
• Refractive Index: n20/D 1.4615(lit.)
• Boiling Point: 222.4 °C at 760 mmHg
• PKA: 15.16±0.10(Predicted)
• Flash Point: 65.6 °C
• PSA: 46.25000
• Density: 0.919 g/cm³
• LogP: 0.80800
• Storage Temp.: 2-8°C
• Sensitive.: Air Sensitive
• Solubility.: Chloroform, Ethyl Acetate
• Water Solubility.: miscible
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 103.099714038
• Heavy Atom Count: 7
• Complexity: 31.3

Purity/Quality:

97% ^*data from raw suppliers

5-Amino-1-pentanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 22-34-35
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Amino Alcohols, Other
• Canonical SMILES: C(CCN)CCO
• Description: 5-Amino-1-pentanol is a linker containing a hydroxyl group and amine group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
• Uses: 5-Amino-1-pentanol is an aliphatic amino alcohol with potential plasma lipid-lowering properties. 5-Amino-1-pentanol and other amino alcohols are used as emulsifying agents in dry-cleaning soaps, wax removers, cosmetics, paints and insecticides. 5-Amino-1-pentanol has been used in the synthesis of S-glycosyl amino-acid building blocks. It has been used as starting reagent in the synthesis of aminofunctionalized 4-chloro-2,2′:6′,2′′-terpyridine.

Technology Process of 5-Aminopentan-1-ol

There total 39 articles about 5-Aminopentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N'-(5-hydroxy-pentyl)-N,N-dibenzyl-formamidine → 5-hydroxypentylamine (2508-29-4)

Guidance literature:

In water; tert-butyl alcohol; at 20 ℃; for 24h;

DOI:10.1021/jo980099g

Reference yield: 99.0%

N-(tert-butyloxycarbonyl)-5-aminopentanol (75178-90-4) → 5-hydroxypentylamine (2508-29-4)

Guidance literature:

With water; at 100 ℃; for 4.5h;

DOI:10.1039/b910239f

Reference yield: 93.0%

tetrahydro-2H-2-pyranol (694-54-2) → 5-hydroxypentylamine (2508-29-4)

Guidance literature:

With ammonium hydroxide; hydrogen; In water; at 80 ℃; for 6h; under 15001.5 Torr; Pressure; Temperature;

upstream raw materials:

TETRAHYDROFURFURYLAMINE

1,5-dibromo-pentane

potassium phtalimide

5-hydroxypentanal

Downstream raw materials:

1-amino-5-cyanopentane

piperidine

1-Amino-5-bromopentane

1-benzoylamino-5-benzoyloxy-pentane