3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)-

Base Information

Chemical Name:3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)-
CAS No.:942144-14-1
Molecular Formula:C₂₂H₄₃NO₄Si
Molecular Weight:413.673
Hs Code.:
Mol file:942144-14-1.mol

Synonyms:3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)-

Suppliers and Price of 3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-tert-Butyl4-((R)-2-(((tert-butyldimethylsilyl)oxy)methyl)pent-4-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate 95+%
1g
$ 772.00

Chemenu
tert-butyl(S)-4-((R)-2-(((tert-butyldimethylsilyl)oxy)methyl)pent-4-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate 95%
1g
$ 729.00

American Custom Chemicals Corporation
(S)-TERT-BUTYL-4-((R)-2-(((TERT-BUTYLDIMETHYLSILYL)OXY)METHYL)PENT-4-EN-1-YL)-2,2-DIMETHYLOXAZOLIDINE-3-CARBOXYLATE 95.00%
5MG
$ 496.06

Total 4 raw suppliers

Chemical Property of 3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)-

Chemical Property:

PSA：48.00000
LogP:5.90050
Storage Temp.:2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

(S)-tert-Butyl4-((R)-2-(((tert-butyldimethylsilyl)oxy)methyl)pent-4-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)-

There total 4 articles about 3-Oxazolidinecarboxylic acid, 4-[(2R)-2-[[[(1,1-diMethylethyl)diMethylsilyl]oxy]Methyl]-4-penten-1-yl]-2,2-diMethyl-, 1,1-diMethylethyl ester, (4S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 942144-13-0
(S)-tert-butyl 4-((R)-2-(hydroxymethyl)pent-4-enyl)-2,2-dimethyloxazolidine-3-carboxylate

: 18162-48-6
tert-butyldimethylsilyl chloride

: 942144-14-1
(S)-tert-butyl 4-((R)-2-((tert-butyldimethylsilyloxy)methyl)pent-4-enyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: With 1H-imidazole; dmap; In dichloromethane; at 20 ℃;

Reference yield:

: 942144-12-9
tert-butyl (2S,4R)-1-hydroxy-4-(hydroxymethyl)hept-6-en-2-ylcarbamate

: 942144-14-1
(S)-tert-butyl 4-((R)-2-((tert-butyldimethylsilyloxy)methyl)pent-4-enyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / acetone / 1 h / -20 - 20 °C

2: 1H-imidazole; dmap / dichloromethane / 16 h / 20 °C

With 1H-imidazole; dmap; toluene-4-sulfonic acid; In dichloromethane; acetone;
DOI:10.1021/ml200137x

Reference yield:

: 144978-35-8,144978-12-1,251924-83-1
(S)-ethyl N-tert-butoxycarbonylpyroglutamate

: 942144-14-1
(S)-tert-butyl 4-((R)-2-((tert-butyldimethylsilyloxy)methyl)pent-4-enyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran; hexane / 1 h / -78 °C

1.2: 2 h / -78 °C

2.1: sodium tetrahydroborate / methanol; water / 1 h / 20 °C

3.1: toluene-4-sulfonic acid / acetone / 1 h / -20 - 20 °C

4.1: 1H-imidazole; dmap / dichloromethane / 16 h / 20 °C

With 1H-imidazole; dmap; sodium tetrahydroborate; toluene-4-sulfonic acid; lithium hexamethyldisilazane; In tetrahydrofuran; methanol; hexane; dichloromethane; water; acetone;
DOI:10.1021/ml200137x