(2-Phenyl-1,3-thiazol-5-yl)methanol

Base Information

Chemical Name:(2-Phenyl-1,3-thiazol-5-yl)methanol
CAS No.:859485-91-9
Molecular Formula:C10H9NOS
Molecular Weight:191.254
Hs Code.:2934100090
European Community (EC) Number:827-026-2
Mol file:859485-91-9.mol

Synonyms:(2-phenyl-1,3-thiazol-5-yl)methanol;859485-91-9;(2-Phenylthiazol-5-yl)methanol;(2-Phenyl-thiazol-5-yl)-methanol;2-phenyl-5-Thiazolemethanol;SCHEMBL1895825;RTGLBURQTRPWRA-UHFFFAOYSA-N;MFCD09694149;AKOS000321111;AS-8446;MCULE-6014380293;DB-423630;CS-0258665;EN300-70786;F83352;Z336081052

Suppliers and Price of (2-Phenyl-1,3-thiazol-5-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(2-phenyl-1,3-thiazol-5-yl)methanol
10mg
$ 60.00

TRC
(2-phenyl-1,3-thiazol-5-yl)methanol
5mg
$ 45.00

SynQuest Laboratories
(2-Phenyl-1,3-thiazol-5-yl)methanol
1 g
$ 332.00

Matrix Scientific
(2-Phenyl-1,3-thiazol-5-yl)methanol
500mg
$ 252.00

Matrix Scientific
(2-Phenyl-1,3-thiazol-5-yl)methanol
1g
$ 315.00

Matrix Scientific
(2-Phenyl-1,3-thiazol-5-yl)methanol
5g
$ 1050.00

Chemenu
(2-Phenylthiazol-5-yl)methanol 95%
5g
$ 711.00

American Custom Chemicals Corporation
(2-PHENYL-1,3-THIAZOL-5-YL)METHANOL 95.00%
5MG
$ 498.14

Alichem
(2-Phenylthiazol-5-yl)methanol
25g
$ 1420.40

Alichem
(2-Phenylthiazol-5-yl)methanol
10g
$ 871.00

Total 7 raw suppliers

Chemical Property of (2-Phenyl-1,3-thiazol-5-yl)methanol

Chemical Property:

Melting Point:76-77 °C(Solv: ligroine (8032-32-4); ethanol (64-17-5)(6:1))
Boiling Point:372.2±34.0 °C(Predicted)
PKA:13.54±0.10(Predicted)
PSA：61.36000
Density:1.264±0.06 g/cm3(Predicted)
LogP:2.30240
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:191.04048508
Heavy Atom Count:13
Complexity:159

Purity/Quality:

99%, ^*data from raw suppliers

(2-phenyl-1,3-thiazol-5-yl)methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC=C(S2)CO

Technology Process of (2-Phenyl-1,3-thiazol-5-yl)methanol

There total 3 articles about (2-Phenyl-1,3-thiazol-5-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1011-40-1
2-phenyl-1,3-thiazole-5-carbaldehyde

: 859485-91-9
5-hydroxymethyl-2-phenylthiazole

Guidance literature:: With sodium tetrahydroborate; In ethanol; at 0 - 20 ℃; for 0.5h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.0c01372

Reference yield:

: 172678-67-0
ethyl 2-phenyl-1,3-thiazole-5-carboxylate

: 859485-91-9
5-hydroxymethyl-2-phenylthiazole

Guidance literature:: With lithium aluminium tetrahydride; diethyl ether;

Reference yield:

: 98-80-6
phenylboronic acid

: 859485-91-9
5-hydroxymethyl-2-phenylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / 1,4-dioxane; water / 100 °C / Inert atmosphere

2: sodium tetrahydroborate; methanol / 1 h / 20 °C

With methanol; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium tetrahydroborate; potassium carbonate; In 1,4-dioxane; water;
DOI:10.1021/acs.orglett.9b00563