1011-40-1

Basic information

• Product Name: 2-PHENYL-1,3-THIAZOLE-5-CARBALDEHYDE
• Synonyms: 2-PHENYL-THIAZOLE-5-CARBALDEHYDE;2-PHENYL-1,3-THIAZOLE-5-CARBALDEHYDE;CHEMBRDG-BB 4301192;2-PHENYLTHIAZOLE-5-CARBALDEHYDE, 95+%;2-phenyl-1,3-thiazole-5-carbaldehyde(SALTDATA: FREE);2-Phenyl-5-forMylthiazole;2-Phenylthiazole-5-carboxaldehyde;5-Thiazolecarboxaldehyde,2-phenyl-
• CAS NO: 1011-40-1
• Molecular Formula: C₁₀H₇NOS
• Molecular Weight: 189.23
• Product Categories: API intermediates
• Mol File: 1011-40-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 78-80°C
• Boiling Point: 352.977 °C at 760 mmHg
• Flash Point: 167.275 °C
• Appearance: /
• Density: 1.269 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.645
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.65±0.10(Predicted)
• CAS DataBase Reference: 2-PHENYL-1,3-THIAZOLE-5-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYL-1,3-THIAZOLE-5-CARBALDEHYDE(1011-40-1)
• EPA Substance Registry System: 2-PHENYL-1,3-THIAZOLE-5-CARBALDEHYDE(1011-40-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 1011-40-1(Hazardous Substances Data)

Usage

General Description

2-Phenyl-1,3-thiazole-5-carbaldehyde is a chemical compound with the molecular formula C11H7NOS. It is a yellow powder and is often used as a building block in organic synthesis. 2-PHENYL-1,3-THIAZOLE-5-CARBALDEHYDE is known for its aromatic and thiazole ring, which makes it highly versatile for use in various chemical reactions. It is also used in the production of pharmaceuticals, agrochemicals, and materials science. Moreover, it has potential applications in the field of medicine and drug discovery due to its unique structural features. Additionally, it can be used as a reagent in chemical research and has been the subject of various scientific studies.

InChI:InChI=1/C10H7NOS/c12-7-9-6-11-10(13-9)8-4-2-1-3-5-8/h1-7H

Upstream product

• 859485-91-9 5-hydroxymethyl-2-phenylthiazole 
• 172678-67-0 ethyl 2-phenyl-1,3-thiazole-5-carboxylate 
• 98-80-6 phenylboronic acid 
• 464192-28-7 2-bromo-1,3-thiazole-5-carbaldehyde 
• 36437-19-1 2-chloromalonaldehyde 
• 2227-79-4 benzenecarbothioamide 

Downstream Products

• 859485-91-9 5-hydroxymethyl-2-phenylthiazole 
• 1826-11-5 2-phenylthiazole 
• 912369-14-3 tert-butyl (3S)-3-[(7-cyano-2-phenyl[1,3]thiazolo[4,5-c]pyridin-4-yl)amino]piperidine-1-carboxylate 
• 690635-66-6 4-oxo-2-phenyl-4,5-dihydro-thiazolo[4,5-c]pyridine-7-carbonitrile 
• 690635-65-5 4-chloro-2-phenyl[1,3]thiazolo[4,5-c]pyridine-7-carbonitrile 
• 690635-64-4 7-bromo-2-phenyl[1,3]thiazolo[4,5-c]pyridin-4(5H)-one 
• 690635-63-3 2-phenyl[1,3]thiazolo[4,5-c]pyridin-4(5H)-one 
• 1311195-97-7 (2-phenylthiazol-5-yl)(3,4,5-trimethoxyphenyl)methanol 
• 1311195-65-9 (2-phenylthiazol-5-yl)(3,4,5-trimethoxyphenyl)methanone 
• 1235472-05-5 4-amino-5-cyano-6-ethoxy-N-((1-((2-phenylthiazol-5-yl)methyl)piperidin-4-yl)methyl)picolinamide 
• 1195985-33-1 (R)-1-phenyl-N-((2-phenyl-1,3-thiazol-5-yl)methyl)ethanamine 
• 946501-52-6 2,2,2-trifluoro-1-(2-phenyl-1,3-thiazol-5-yl)ethanol 
• 787548-92-9 3-(2-phenyl-thiazol-5-yl)-4-{2-[3-(5,6,7,8-tetrahydro-[1,8]naphthyridin-2-yl)-propyl]-thiazol-4-yl}-butyric acid ethyl ester 
• 722549-34-0 ethyl 6-chloro-5-oxo-3-(2-phenyl-1,3-thiazol-5-yl)hexanoate 

Relevant articles and documents

THIAZOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS

Provided herein are compounds of Formula (I) and Formula (II) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.

2,4-Imidazolinedione heterocyclic derivative, and preparation method and use thereof

The invention belongs to the field of chemical medicines, and concretely relates to a 2,4-imidazolinedione heterocyclic derivative, and a preparation method and a use thereof. The structure of the 2,4-imidazolinedione heterocyclic derivative is represented by formula I. The invention also provides the preparation method and the use of the 2,4-imidazolinedione heterocyclic derivative. The 2,4-imidazolinedione heterocyclic derivative has a good inhibition effect on Pim-1 protein kinase micro-molecules, and has important exploitation application prospect.

Antiinflammation agents

Compounds, compositions and methods that are useful in the treatment of inflammatory, immunoregulatory, metabolic, infectious and cell proliferative diseases or conditions are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of proteins involved in inflammation, metabolism, infection and cell proliferation. The subject compounds contain a fused heterobicyclic ring.