D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine

Base Information

Chemical Name:D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine
CAS No.:1329795-88-1
Molecular Formula:C₂₄H₃₃NO₃
Molecular Weight:383.531
Hs Code.:
Mol file:1329795-88-1.mol

Synonyms:D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine;1-[1-(4-Methoxyphenyl)]-2-[((2-(4-Methoxyphenyl)ethyl)aMino)ethyl]cyclohexanol;Venlafaxine EP IMpurity H

Suppliers and Price of D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl)Venlafaxine
100mg
$ 1355.00

A2B
D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl)Venlafaxine
100mg
$ 1257.00

A2B
D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl)Venlafaxine
10mg
$ 290.00

Total 20 raw suppliers

Chemical Property of D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine

Chemical Property:

PSA：50.72000
LogP:4.70580
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl)Venlafaxine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An impurity of Venlafaxine (V120000). D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine (Venlafaxine EP Impurity H (BASE)) is an impurity of Venlafaxine (V120000).

Technology Process of D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine

There total 4 articles about D,L-N,N-Didesmethyl-N-(4-methoxyphenethyl) Venlafaxine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.5%

: 93413-77-5,272788-06-4,273720-73-3,149289-31-6
N,N-didesmethylvenlafaxine

: 73735-36-1
methanesulfonic acid-2-(4-methoxyphenyl)ethyl ester

: 1329795-88-1
(±)-1-{2-[(4-methoxyphenethyl)amino]-1-(4-methoxyphenyl)ethyl}cyclohexanol

Guidance literature:: With sodium hydrogencarbonate; In water; acetonitrile; Solvent; Reagent/catalyst; Reflux;

Reference yield:

: 104-01-8
4-Methoxyphenylacetic acid

: 1329795-88-1
(±)-1-{2-[(4-methoxyphenethyl)amino]-1-(4-methoxyphenyl)ethyl}cyclohexanol

Guidance literature:: Multi-step reaction with 3 steps

1: boron trifluoride diethyl etherate; sodium tetrahydroborate / tetrahydrofuran / 20 °C

2: triethylamine / dichloromethane / 20 °C

3: sodium hydrogencarbonate / acetonitrile; water / Reflux

With sodium tetrahydroborate; boron trifluoride diethyl etherate; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; dichloromethane; water; acetonitrile;

Reference yield:

: 104-47-2
p-methoxybenzylnitrile

: 1329795-88-1
(±)-1-{2-[(4-methoxyphenethyl)amino]-1-(4-methoxyphenyl)ethyl}cyclohexanol

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide; water / ethanol / Reflux

2: boron trifluoride diethyl etherate; sodium tetrahydroborate / tetrahydrofuran / 20 °C

3: triethylamine / dichloromethane / 20 °C

4: sodium hydrogencarbonate / acetonitrile; water / Reflux

With sodium tetrahydroborate; boron trifluoride diethyl etherate; water; sodium hydrogencarbonate; triethylamine; sodium hydroxide; In tetrahydrofuran; ethanol; dichloromethane; water; acetonitrile;