2-(5-Methyl-2-thienyl)ethanamine

Base Information

• Chemical Name: 2-(5-Methyl-2-thienyl)ethanamine
• CAS No.: 30433-92-2
• Molecular Formula: C7H11NS
• Molecular Weight: 141.237
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID00564036
• Wikidata: Q82448605
• Mol file: 30433-92-2.mol

Synonyms:30433-92-2;2-(5-Methyl-2-thienyl)ethanamine;2-(5-Methyl-thiophen-2-yl)-ethylamine;2-(5-methylthiophen-2-yl)ethanamine;2-Thiopheneethanamine, 5-methyl-;2-(5-Methylthiophen-2-yl)ethan-1-amine;MFCD08059759;2-(5-methylthiophen-2-yl)ethylamine;SCHEMBL1362788;DTXSID00564036;VAYWLNRNWZOIAG-UHFFFAOYSA-N;2-(5-methylthien-2-yl)-ethylamine;AKOS000303358;AS-31354;BP-10451;SY024090;CS-0450730;EN300-1240679;A876194

Chemical Property of 2-(5-Methyl-2-thienyl)ethanamine

Chemical Property:

• Vapor Pressure: 0.139mmHg at 25°C
• Boiling Point: 216.593°C at 760 mmHg
• Flash Point: 84.793°C
• PSA: 54.26000
• Density: 1.073g/cm³
• LogP: 2.25800
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 141.06122053
• Heavy Atom Count: 9
• Complexity: 85

Purity/Quality:

97% ^*data from raw suppliers

2-(5-Methyl-2-thienyl)ethanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(S1)CCN

Technology Process of 2-(5-Methyl-2-thienyl)ethanamine

There total 2 articles about 2-(5-Methyl-2-thienyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

2-methyl-5-(E-2-nitroethenyl)thiophene (117693-20-6) → 2-(5-methylthiophen-2-yl)ethan-1-amine (30433-92-2)

Guidance literature:

2-methyl-5-(E-2-nitroethenyl)thiophene; With lithium aluminium tetrahydride; In diethyl ether; at 20 - 25 ℃; for 5h; Heating / reflux;

With sodium hydroxide; water; In diethyl ether; at 0 ℃;

Reference yield: 20.0%

2-methyl-5-(2-nitro-vinyl)-thiophene (30433-88-6) → 2-(5-methylthiophen-2-yl)ethan-1-amine (30433-92-2)

Guidance literature:

2-methyl-5-(2-nitro-vinyl)-thiophene; With lithium aluminium tetrahydride; In diethyl ether; for 0.0833333h;

With Rochelle's salt; In diethyl ether; water;

Reference yield: 90.0%

2-(5-methylthiophen-2-yl)ethan-1-amine (30433-92-2) + benzoyl chloride (98-88-4) → C14H15NOS

Guidance literature:

With sodium hydroxide; In water; for 12h; Cooling with ice;

upstream raw materials:

2-methyl-5-(E-2-nitroethenyl)thiophene

2-methyl-5-(2-nitro-vinyl)-thiophene

Downstream raw materials:

N-[2-(5-methyl-thiophen-2-yl)-ethyl]-3-(4-trifluoromethyl-phenyl)-propionamide

2-methyl-4-phenyl-4,5,6,7-tetrahydrothieno-[3,2-c]pyridine