Chroman-2-ylmethanamine

Base Information

Chemical Name:Chroman-2-ylmethanamine
CAS No.:3990-59-8
Molecular Formula:C₁₀H₁₃NO
Molecular Weight:163.219
Hs Code.:
European Community (EC) Number:961-968-6
DSSTox Substance ID:DTXSID50460438
Mol file:3990-59-8.mol

Synonyms:Chroman-2-ylmethanamine;3990-59-8;(Chroman-2-yl)methanamine;1-(3,4-DIHYDRO-2H-CHROMEN-2-YL)METHANAMINE;3,4-dihydro-2H-chromen-2-ylmethanamine;MFCD10697678;2-aminomethyl-chromane;aminomethylchroman;2-(aminomethyl)chroman;(-)-2-aminomethylchroman;SCHEMBL430983;AMY4302;DTXSID50460438;BSRHATGBRQMDRF-UHFFFAOYSA-N;C-CHROMAN-2-YL-METHYLAMINE;AKOS006302509;AB60224;SB45185;SB46149;2-aminomethyl-3,4-dihydro-2H-chromene;BS-17009;SY240524;CS-0155925;FT-0690926;FT-0722342;EN300-313349;(3,4-dihydro-2H-1-benzopyran-2-yl)methanamine;A924941;(+/-)-3,4-dihydro-2H-1-benzopyran-2-methanamine;(+/-)-[(3,4-dihydro-2H-1-benzopyran-2-yl)methyl]amine

Suppliers and Price of Chroman-2-ylmethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
(Chroman-2-yl)methanamine 95%
1g
$ 2017.00

Matrix Scientific
(Chroman-2-yl)methanamine 95%
500mg
$ 1258.00

Crysdot
Chroman-2-ylmethanamine 95+%
25g
$ 280.00

Crysdot
Chroman-2-ylmethanamine 95+%
5g
$ 90.00

Crysdot
Chroman-2-ylmethanamine 95+%
10g
$ 140.00

Crysdot
Chroman-2-ylmethanamine 95+%
100g
$ 750.00

Chemenu
Chroman-2-ylmethanamine 95%
100g
$ 701.00

Ambeed
Chroman-2-ylmethanamine 95%
5g
$ 1260.00

Ambeed
Chroman-2-ylmethanamine 95%
250mg
$ 132.00

Ambeed
Chroman-2-ylmethanamine 95%
100mg
$ 88.00

Total 12 raw suppliers

Chemical Property of Chroman-2-ylmethanamine

Chemical Property:

Boiling Point:279.0±9.0 °C(Predicted)
PKA:9.14±0.29(Predicted)
PSA：35.25000
Density:1.073±0.06 g/cm3(Predicted)
LogP:2.03920
Storage Temp.:2-8°C(protect from light)
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:163.099714038
Heavy Atom Count:12
Complexity:149

Purity/Quality:

97% ^*data from raw suppliers

(Chroman-2-yl)methanamine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=CC=CC=C2OC1CN

Technology Process of Chroman-2-ylmethanamine

There total 7 articles about Chroman-2-ylmethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 3990-58-7
chroman-2-ylcarboxamide

: 3990-59-8,144980-39-2,144980-40-5
2-(aminomethyl)chromane

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 20h;
DOI:10.1021/jm400894u

Reference yield:

: 51939-71-0
chroman-2-carboxylic acid

: 3990-59-8,144980-39-2,144980-40-5
2-(aminomethyl)chromane

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-hydroxybenzotriazole; N-(dimethylaminopropyl)-N'-ethylcarbodiimide / CH₂Cl₂; dimethylformamide / 0.5 h / 23 °C

1.2: aq. NH₃ / dimethylformamide; CH₂Cl₂ / 16 h / 23 °C

2.1: 3.50 g / LiAlH₄ / tetrahydrofuran / 20 h / 23 °C

With lithium aluminium tetrahydride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm040124c

Reference yield:

: 403704-70-1
2-aminomethyl-4-chromanone

: 3990-59-8,144980-39-2,144980-40-5
2-(aminomethyl)chromane

Guidance literature:: 2-aminomethyl-4-chromanone; With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 5.5h; Heating / reflux;

With water; In tetrahydrofuran; at 0 ℃;