N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2-(2-methoxy-5-methyl-N-methylsulfonylanilino)acetamide

Base Information

Chemical Name:N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2-(2-methoxy-5-methyl-N-methylsulfonylanilino)acetamide
CAS No.:6467-37-4
Molecular Formula:C14H16 O5
Molecular Weight:458.5306
Hs Code.:
DSSTox Substance ID:DTXSID60359788
Wikidata:Q82141147

Synonyms:6467-37-4;AH-487/15582377;N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2-(2-methoxy-5-methyl-N-methylsulfonylanilino)acetamide;CBKinase1_000618;CBKinase1_013018;DTXSID60359788;STK120282;AKOS000376564;EU-0046013;BRD-K42597154-001-01-2;N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-2-[2-methoxy-5-methyl(methylsulfonyl)anilino]acetamide;N-(1,5-DIMETHYL-3-OXO-2-PHENYL-2,3-DIHYDRO-1H-PYRAZOL-4-YL)-2-[N-(2-METHOXY-5-METHYLPHENYL)METHANESULFONAMIDO]ACETAMIDE;N-(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-N~2~-(2-methoxy-5-methylphenyl)-N~2~-(methylsulfonyl)glycinamide

Suppliers and Price of N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2-(2-methoxy-5-methyl-N-methylsulfonylanilino)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2-(2-methoxy-5-methyl-N-methylsulfonylanilino)acetamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.37g/cm³
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:458.16239112
Heavy Atom Count:32
Complexity:847

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)OC)N(CC(=O)NC2=C(N(N(C2=O)C3=CC=CC=C3)C)C)S(=O)(=O)C

Technology Process of N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2-(2-methoxy-5-methyl-N-methylsulfonylanilino)acetamide

There total 4 articles about N-(1,5-dimethyl-3-oxo-2-phenylpyrazol-4-yl)-2-(2-methoxy-5-methyl-N-methylsulfonylanilino)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1447024-79-4
C₁₅H₂₀O₅

: 6467-37-4
3-Methoxy-4-<2-methylen-butyryl>-phenoxyessigsaeure

Guidance literature:: With potassium carbonate; In ethanol; water; for 24h; Reflux;
DOI:10.1016/j.crci.2013.03.020

Reference yield:

: 150-19-6
O-methylresorcine

: 6467-37-4
3-Methoxy-4-<2-methylen-butyryl>-phenoxyessigsaeure

Guidance literature:: Multi-step reaction with 3 steps

1: aluminum (III) chloride / carbon disulfide

2: potassium carbonate / toluene / 48 h / Reflux

3: potassium carbonate / ethanol; water / 24 h / Reflux

With aluminum (III) chloride; potassium carbonate; In carbon disulfide; ethanol; water; toluene; 1: |Friedel-Crafts Acylation / 3: |Aldol Condensation;
DOI:10.1016/j.crci.2013.03.020

Reference yield:

: 1-(4-hydroxy-2-methoxy-phenyl)-butan-1-one

: 6467-37-4
3-Methoxy-4-<2-methylen-butyryl>-phenoxyessigsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / toluene / 48 h / Reflux

2: potassium carbonate / ethanol; water / 24 h / Reflux

With potassium carbonate; In ethanol; water; toluene; 2: |Aldol Condensation;
DOI:10.1016/j.crci.2013.03.020