4-Phenyl-1H-pyrazole-5-carboxylic acid

Base Information

• Chemical Name: 4-Phenyl-1H-pyrazole-5-carboxylic acid
• CAS No.: 856061-36-4
• Molecular Formula: C₁₀H₈N₂O₂
• Molecular Weight: 188.186
• Hs Code.: 2933199090
• Mol file: 856061-36-4.mol

Synonyms:4-Phenyl-1H-pyrazole-5-carboxylic acid

Chemical Property of 4-Phenyl-1H-pyrazole-5-carboxylic acid

Chemical Property:

• PSA: 65.98000
• LogP: 1.77490

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Phenyl-1H-pyrazole-5-carboxylic acid

There total 3 articles about 4-Phenyl-1H-pyrazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-phenyl-1H-pyrazole-3-carboxylic acid (7510-56-7,856061-36-4)

Guidance literature:

With carbon dioxide; water; permanganate(VII) ion;

Reference yield:

cinnamonitrile (4360-47-8) → 4-phenyl-1H-pyrazole-3-carboxylic acid (7510-56-7,856061-36-4)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / und Behandlung des Reaktionsprodukts mit Brom in CHCl₃ im Sonnenlicht

2: aqueous HCl

With hydrogenchloride; diethyl ether;

Reference yield:

→ 4-phenyl-1H-pyrazole-3-carboxylic acid (7510-56-7,856061-36-4)

Guidance literature:

Benzoylaceton, Diazoessigsaeure-ethylester (sd. ethanol. KOH), Hydrolyse mit 2n NaOH; (geringe Ausbeute);

DOI:10.1039/jr9600001588

upstream raw materials:

cinnamonitrile

Downstream raw materials:

4-phenyl-1H-pyrazole

1-methyl-4-phenyl-1H-pyrazole