(S)-b-AMino-3-Methyl-benzeneethanol

Base Information

Chemical Name:(S)-b-AMino-3-Methyl-benzeneethanol
CAS No.:1026230-99-8
Molecular Formula:C9H13NO
Molecular Weight:151.208
Hs Code.:
Mol file:1026230-99-8.mol

Synonyms:(S)-b-AMino-3-Methyl-benzeneethanol;(2S)-2-AMINO-2-(3-METHYLPHENYL)ETHAN-1-OL;(S)-2-Amino-2-(m-tolyl)ethanol

Suppliers and Price of (S)-b-AMino-3-Methyl-benzeneethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-Amino-2-(m-tolyl)ethanol 95+%
1g
$ 327.00

Crysdot
(S)-2-Amino-2-(m-tolyl)ethanol 95+%
5g
$ 980.00

Chemenu
(S)-2-Amino-2-(m-tolyl)ethanol 95%
5g
$ 926.00

American Custom Chemicals Corporation
(2S)-2-AMINO-2-(3-METHYLPHENYL)ETHAN-1-OL 95.00%
5MG
$ 496.47

Ambeed
(S)-2-Amino-2-(m-tolyl)ethanol 95%
1g
$ 271.00

Ambeed
(S)-2-Amino-2-(m-tolyl)ethanol 95%
250mg
$ 126.00

Ambeed
(S)-2-Amino-2-(m-tolyl)ethanol 95%
100mg
$ 74.00

Ambeed
(S)-2-Amino-2-(m-tolyl)ethanol 95%
5g
$ 1001.00

Alichem
(2S)-2-Amino-2-(3-methylphenyl)ethan-1-olhydrochloride
500mg
$ 980.00

Alichem
(2S)-2-Amino-2-(3-methylphenyl)ethan-1-olhydrochloride
250mg
$ 680.00

Total 5 raw suppliers

Chemical Property of (S)-b-AMino-3-Methyl-benzeneethanol

Chemical Property:

Melting Point:85-87 °C
Boiling Point:300.9±27.0 °C(Predicted)
PKA:12.63±0.10(Predicted)
PSA：46.25000
Density:1.076±0.06 g/cm3(Predicted)
LogP:1.68740
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99%, ^*data from raw suppliers

(S)-2-Amino-2-(m-tolyl)ethanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-b-AMino-3-Methyl-benzeneethanol

There total 5 articles about (S)-b-AMino-3-Methyl-benzeneethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1312719-14-4
(Rs,1S)-N-(2-(tert-butyldimethylsilyloxy)-1-m-tolylethyl)-2-methylpropane-2-sulfinamide

: 1026230-99-8
(S)-2-amino-2-(m-tolyl)ethanol

Guidance literature:: (Rs,1S)-N-(2-(tert-butyldimethylsilyloxy)-1-m-tolylethyl)-2-methylpropane-2-sulfinamide; With hydrogenchloride; In methanol; at 20 ℃; for 3h;

With sodium hydrogencarbonate; In water;
DOI:10.1016/j.tetasy.2011.01.011

Reference yield:

: 704898-29-3,1195902-12-5,20697-03-4
3-methylstyrene oxide

: 1026230-99-8
(S)-2-amino-2-(m-tolyl)ethanol

: 97590-55-1
(R)-2-Amino-1-m-tolyl-ethanol

Guidance literature:: 3-methylstyrene oxide; With (R,R)-Jacobsen catalyst; water; In tetrahydrofuran; at 0 - 22 ℃; for 16h; Inert atmosphere;

With N-[(tert-butoxy)carbonyl]-4-methylbenzenesulfonamide; oxygen; In tetrahydrofuran; at 22 ℃; for 72h; Further stages; Inert atmosphere;
DOI:10.1021/acs.orglett.7b01886

Reference yield:

: 591-17-3
meta-bromotoluene

: 1026230-99-8
(S)-2-amino-2-(m-tolyl)ethanol

Guidance literature:: Multi-step reaction with 4 steps

1.1: magnesium; ethylene dibromide / tetrahydrofuran / 0.67 h / 20 °C / Inert atmosphere

1.2: 3 h / 0 °C / Inert atmosphere

2.1: titanium(IV) isopropylate / tetrahydrofuran / Inert atmosphere; Reflux

3.1: diisobutylaluminium hydride / tetrahydrofuran; toluene / 1 h / -78 °C

3.2: -78 - 20 °C

4.1: hydrogenchloride / methanol / 3 h / 20 °C

With titanium(IV) isopropylate; hydrogenchloride; diisobutylaluminium hydride; magnesium; ethylene dibromide; In tetrahydrofuran; methanol; toluene;
DOI:10.1016/j.tetasy.2011.01.011