Tert-butyl 3-(pyridin-2-yl)azetidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 3-(pyridin-2-yl)azetidine-1-carboxylate
CAS No.:206446-39-1
Molecular Formula:C₁₃H₁₈N₂O₂
Molecular Weight:234.298
Hs Code.:
DSSTox Substance ID:DTXSID501202301
Nikkaji Number:J948.292J
Mol file:206446-39-1.mol

Synonyms:tert-butyl 3-(pyridin-2-yl)azetidine-1-carboxylate;206446-39-1;tert-butyl 3-pyridin-2-ylazetidine-1-carboxylate;3-Pyridin-2-yl-azetidine-1-carboxylic acid tert-butyl ester;SCHEMBL2998444;WOZILFWABRXAFR-UHFFFAOYSA-N;DTXSID501202301;MFCD20528714;AKOS027338169;SB51860;AS-48597;F51809;tert-butyl3-(pyridin-2-yl)azetidine-1-carboxylate;J-524503;1,1-Dimethylethyl 3-(2-pyridinyl)-1-azetidinecarboxylate

Suppliers and Price of Tert-butyl 3-(pyridin-2-yl)azetidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl3-(pyridin-2-yl)azetidine-1-carboxylate 97%
5g
$ 2103.00

Crysdot
tert-Butyl3-(pyridin-2-yl)azetidine-1-carboxylate 97%
1g
$ 699.00

Chemenu
tert-Butyl3-(pyridin-2-yl)azetidine-1-carboxylate 95+%
1g
$ 660.00

Chemenu
tert-Butyl3-(pyridin-2-yl)azetidine-1-carboxylate 95+%
5g
$ 1981.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
3-Pyridin-2-yl-azetidine-1-carboxylicacidtert-butylester 95%+
5g
$ 1225.25

Acints
3-Pyridin-2-yl-azetidine-1-carboxylicacidtert-butylester 95%+
5g
$ 1225.25

Total 5 raw suppliers

Chemical Property of Tert-butyl 3-(pyridin-2-yl)azetidine-1-carboxylate

Chemical Property:

Boiling Point:343.9±35.0 °C(Predicted)
PKA:5.18±0.19(Predicted)
PSA：42.43000
Density:1.133±0.06 g/cm3(Predicted)
LogP:2.35380
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:234.136827821
Heavy Atom Count:17
Complexity:280

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl3-(pyridin-2-yl)azetidine-1-carboxylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CC(C1)C2=CC=CC=N2

Technology Process of Tert-butyl 3-(pyridin-2-yl)azetidine-1-carboxylate

There total 7 articles about Tert-butyl 3-(pyridin-2-yl)azetidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 109-04-6
2-bromo-pyridine

: 206446-38-0
(1-(tert-butoxycarbonyl)azetidin-3-yl)zinc(II) iodide

: 206446-39-1
1-tert-butyl 3-(pyridine-2-yl)azetidine-1-carboxylate

Guidance literature:: (1-(tert-butoxycarbonyl)azetidin-3-yl)zinc(II) iodide; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 0.166667h; Inert atmosphere;

2-bromo-pyridine; In tetrahydrofuran; at 65 ℃; for 2h; Inert atmosphere;

Reference yield: 71.0%

: 109-04-6
2-bromo-pyridine

: 254454-54-1
tert-butyl-3-iodoazetidine-1-carboxylate

: 206446-39-1
1-tert-butyl 3-(pyridine-2-yl)azetidine-1-carboxylate

Guidance literature:: tert-butyl-3-iodoazetidine-1-carboxylate; With lithium chloride; zinc; In tetrahydrofuran; at 110 ℃; Flow reactor;

2-bromo-pyridine; In tetrahydrofuran; at 60 ℃; Flow reactor;
DOI:10.1002/adsc.201400243