7-Azaspiro[3.5]nonane-7-carboxylic acid, 1,1-dichloro-2-oxo-, phenylMethyl ester

Base Information

Chemical Name:7-Azaspiro[3.5]nonane-7-carboxylic acid, 1,1-dichloro-2-oxo-, phenylMethyl ester
CAS No.:147610-97-7
Molecular Formula:C16H17Cl2NO3
Molecular Weight:342.222
Hs Code.:2933990090
Mol file:147610-97-7.mol

Synonyms:7-Azaspiro[3.5]nonane-7-carboxylic acid, 1,1-dichloro-2-oxo-, phenylMethyl ester

Suppliers and Price of 7-Azaspiro[3.5]nonane-7-carboxylic acid, 1,1-dichloro-2-oxo-, phenylMethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate 95+%
1g
$ 412.00

Chemenu
benzyl1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate 95%
1g
$ 389.00

American Custom Chemicals Corporation
BENZYL-1,1-DICHLORO-2-OXO-7-AZASPIRO[3.5]NONANE-7-CARBOXYLATE 95.00%
5MG
$ 504.05

Alichem
Benzyl1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate
1g
$ 442.38

Total 6 raw suppliers

Chemical Property of 7-Azaspiro[3.5]nonane-7-carboxylic acid, 1,1-dichloro-2-oxo-, phenylMethyl ester

Chemical Property:

Boiling Point:493.7±45.0 °C(Predicted)
PKA:-2.24±0.40(Predicted)
PSA：46.61000
Density:1.38±0.1 g/cm3(Predicted)
LogP:3.49000
Storage Temp.:2-8°C

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Benzyl1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-Azaspiro[3.5]nonane-7-carboxylic acid, 1,1-dichloro-2-oxo-, phenylMethyl ester

There total 2 articles about 7-Azaspiro[3.5]nonane-7-carboxylic acid, 1,1-dichloro-2-oxo-, phenylMethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 138163-12-9
benzyl 4-methylene-1-piperidinecarboxylate

: 76-02-8
trifluoroacetyl chloride

: 147610-97-7
benzyl 1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate

Guidance literature:: With zinc-copper couple; In diethyl ether; at 20 ℃; for 2h;

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 147610-97-7
benzyl 1,1-dichloro-2-oxo-7-azaspiro[3.5]nonane-7-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / tetrahydrofuran / 3 h / 16 - 20 °C / Inert atmosphere

2: zinc-copper / tetrahydrofuran / 16.5 h / 15 - 30 °C

With potassium tert-butylate; In tetrahydrofuran;