(1R)-3β-Isopropenyl-2,2-dimethylcyclobutane-1β-methanol acetate

Base Information

Chemical Name:(1R)-3β-Isopropenyl-2,2-dimethylcyclobutane-1β-methanol acetate
CAS No.:28465-10-3
Molecular Formula:C12H20O2
Molecular Weight:196.286
Hs Code.:
Mol file:28465-10-3.mol

Synonyms:(1R)-3β-Isopropenyl-2,2-dimethylcyclobutane-1β-methanol acetate;(1R,3R)-1-Acetoxymethyl-2,2-dimethyl-3-(1-methylethenyl)cyclobutane;[1R,3R,(+)]-2,2-Dimethyl-3-isopropenylcyclobutanemethanol acetate;Acetic acid [(1R)-2,2-dimethyl-3β-isopropenylcyclobutane-1β-yl]methyl ester;(1R,3R)-cis-2,2-Dimethyl-3-isopropenyl-cyclobutanemethanol acetate

Suppliers and Price of (1R)-3β-Isopropenyl-2,2-dimethylcyclobutane-1β-methanol acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 3 raw suppliers

Chemical Property of (1R)-3β-Isopropenyl-2,2-dimethylcyclobutane-1β-methanol acetate

Chemical Property:

PSA：26.30000
LogP:2.78790

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

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Technology Process of (1R)-3β-Isopropenyl-2,2-dimethylcyclobutane-1β-methanol acetate

There total 15 articles about (1R)-3β-Isopropenyl-2,2-dimethylcyclobutane-1β-methanol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 108-24-7
acetic anhydride

: 28465-09-0
(1R-cis)-1-hydroxymethyl-2,2-dimethyl-3-isopropenyl-cyclobutane

: 28465-10-3
(+)-(1R)-cis-2,2-dimethyl-3-isopropenylcyclobutanemethanol acetate

Guidance literature:: With triethylamine; In dichloromethane; for 24h; Ambient temperature;

Reference yield:

: 22571-78-4
(+)-cis-pinononoic acid

: 28465-10-3
(+)-(1R)-cis-2,2-dimethyl-3-isopropenylcyclobutanemethanol acetate

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / diethyl ether / 2 h / cooling

2: 88 percent / n-BuLi / hexane; tetrahydrofuran / 16 h / -30 - 25 °C

3: DIBAH / diethyl ether; toluene / 16 h / 0 - 25 °C

4: 0.2 percent / pyridine / 12.5 h / 0 - 10 °C

With pyridine; n-butyllithium; diisobutylaluminium hydride; In tetrahydrofuran; diethyl ether; hexane; toluene; 2: Wittig reaction;
DOI:10.1007/s10600-006-0082-x

Reference yield:

: 28465-11-4
(1R-cis)-(+)-2,2-dimethyl-3-isopropenyl-cyclobutane carboxylic acid

: 28465-10-3
(+)-(1R)-cis-2,2-dimethyl-3-isopropenylcyclobutanemethanol acetate

Guidance literature:: Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether / 1.5 h / 0 °C

2: 3.03 g / pyridine / 0 - 20 °C

With pyridine; lithium aluminium tetrahydride; In diethyl ether;
DOI:10.1021/jf035301h