Ethyl 2-amino-5-chloro-3-methylbenzoate

Base Information

Chemical Name:Ethyl 2-amino-5-chloro-3-methylbenzoate
CAS No.:1032668-60-2
Molecular Formula:C₁₀H₁₂ClNO₂
Molecular Weight:213.664
Hs Code.:
DSSTox Substance ID:DTXSID801280869
Mol file:1032668-60-2.mol

Synonyms:ETHYL 2-AMINO-5-CHLORO-3-METHYLBENZOATE;1032668-60-2;Benzoic acid, 2-amino-5-chloro-3-methyl-, ethyl ester;SCHEMBL16529438;DTXSID801280869;CS-0348002;FT-0712072;EN300-5444156

Suppliers and Price of Ethyl 2-amino-5-chloro-3-methylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
ethyl2-amino-5-chloro-3-methylbenzoate 95
5g
$ 1467.00

Total 3 raw suppliers

Chemical Property of Ethyl 2-amino-5-chloro-3-methylbenzoate

Chemical Property:

Boiling Point:329.7±37.0 °C(Predicted)
PKA:1.62±0.10(Predicted)
PSA：108.04000
Density:1.225±0.06 g/cm3(Predicted)
LogP:3.72850
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:213.0556563
Heavy Atom Count:14
Complexity:210

Purity/Quality:

98%min ^*data from raw suppliers

ethyl2-amino-5-chloro-3-methylbenzoate 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(C(=CC(=C1)Cl)C)N

Technology Process of Ethyl 2-amino-5-chloro-3-methylbenzoate

There total 4 articles about Ethyl 2-amino-5-chloro-3-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.1%

: 64-17-5
ethanol

: 20776-67-4
2-amino-5-chloro-3-methylbenzoic acid

: 1032668-60-2
2-amino-5-chloro-3-methylbenzoic acid ethyl ester

Guidance literature:: With sulfuric acid; at 5 ℃; for 6h; Reflux;

Reference yield:

: 4389-45-1
3-methylantranilic acid

: 1032668-60-2
2-amino-5-chloro-3-methylbenzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: chlorine / 1,2-dichloro-ethane / 3 h / 50 °C

2: sulfuric acid / 6 h / 5 °C / Reflux

With sulfuric acid; chlorine; In 1,2-dichloro-ethane;

Reference yield:

: 5437-38-7
3-methyl-2-nitrobenzoic acid

: 1032668-60-2
2-amino-5-chloro-3-methylbenzoic acid ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen / ethanol / 4 h / 50 °C / 1500.15 Torr

2: chlorine / 1,2-dichloro-ethane / 3 h / 50 °C

3: sulfuric acid / 6 h / 5 °C / Reflux

With sulfuric acid; hydrogen; chlorine; In ethanol; 1,2-dichloro-ethane;