1-(4-(AMinoMethyl)phenyl)-N,N-diMethylMethanaMine hydrochloride

Base Information

• Chemical Name: 1-(4-(AMinoMethyl)phenyl)-N,N-diMethylMethanaMine hydrochloride
• CAS No.: 242452-35-3
• Molecular Formula: C10H17ClN2
• Molecular Weight: 200.70838
• Mol file: 242452-35-3.mol

Synonyms:1-(4-(AMinoMethyl)phenyl)-N,N-diMethylMethanaMine hydrochloride

Chemical Property of 1-(4-(AMinoMethyl)phenyl)-N,N-diMethylMethanaMine hydrochloride

Chemical Property:

• PSA: 29.26000
• LogP: 2.70920
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1-(4-(Aminomethyl)phenyl)-N,N-dimethylmethanaminehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-(AMinoMethyl)phenyl)-N,N-diMethylMethanaMine hydrochloride

There total 2 articles about 1-(4-(AMinoMethyl)phenyl)-N,N-diMethylMethanaMine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.6%

4-cyano-N,N-dimethylbenzylamine (35525-86-1) → 1-(4-(aminomethyl)phenyl)-N,N-dimethylmethanamine hydrochloride (242452-35-3)

Guidance literature:

With borane-THF; In tetrahydrofuran; for 16h; Reflux; Inert atmosphere;

Reference yield:

4-cyanobenzyl bromide (17201-43-3) → 1-(4-(aminomethyl)phenyl)-N,N-dimethylmethanamine hydrochloride (242452-35-3)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate; triethylamine / tetrahydrofuran / 60 °C

2: borane-THF / tetrahydrofuran / 16 h / Reflux; Inert atmosphere

With borane-THF; potassium carbonate; triethylamine; In tetrahydrofuran;

Reference yield: 19.0%

1-(4-(aminomethyl)phenyl)-N,N-dimethylmethanamine hydrochloride (242452-35-3) + ethyl 4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxylate (1353498-44-8) → N-{4-[(dimethylamino)methyl]benzyl}-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide (1456890-17-7)

Guidance literature:

With triethylamine; In ethanol; at 80 ℃; for 18h; Inert atmosphere;

DOI:10.1021/jm400718n

upstream raw materials:

4-cyano-N,N-dimethylbenzylamine

4-cyanobenzyl bromide

Downstream raw materials:

C₁₇H₂₁ClN₂

N-{4-[(dimethylamino)methyl]benzyl}-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-5-carboxamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 242452-35-3 1-(4-(AMinoMethyl)phenyl)-N,N-diMethylMethanaMine hydrochloride

Send

Send

Metric Ton KG G Pound L ML

Send

Send