(3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylic Acid Methyl Ester

Base Information

Chemical Name:(3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylic Acid Methyl Ester
CAS No.:143308-74-1
Molecular Formula:C13H18O6
Molecular Weight:270.27842
Hs Code.:
Mol file:143308-74-1.mol

Synonyms:(3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylic Acid Methyl Ester;3,4-(Isopropylidenedioxy) ShikiMic Acid Methyl Ester Acetate

Suppliers and Price of (3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylic Acid Methyl Ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4-(Isopropylidenedioxy)ShikimicAcidMethylEsterAcetate
100mg
$ 155.00

Medical Isotopes, Inc.
3,4-(Isopropylidenedioxy)ShikimicAcidMethylEsterAcetate
100 mg
$ 625.00

aablocks
(3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylicAcidMethylEster
1g
$ 1250.00

Total 4 raw suppliers

Chemical Property of (3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylic Acid Methyl Ester

Chemical Property:

PSA：71.06000
LogP:0.94130
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly, Sonicated)

Purity/Quality:

99% ^*data from raw suppliers

3,4-(Isopropylidenedioxy)ShikimicAcidMethylEsterAcetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3,4-(Isopropylidenedioxy) Shikimic acid methyl ester acetate is a derivative of Shikimic acid (S357100).

Technology Process of (3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylic Acid Methyl Ester

There total 30 articles about (3R,4S,5R)-7-(Acetyloxy)-3a,6,7,7a-tetrahydro-2,2-diMethyl-1,3-benzodioxole-5-carboxylic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 88165-26-8
methyl 3,4-O-isopropylideneshikimate

: 108-24-7
acetic anhydride

: 143308-74-1
(3aR,7R,7aS)-methyl 7-acetoxy-2,2-dimethyl-3a,6,7,7atetrahydrobenzo[d][1,3]dioxole-5-carboxylate

Guidance literature:: With dmap; In dichloromethane; for 2h; Ambient temperature;
DOI:10.1021/jo00047a049

Reference yield:

: 40983-58-2
methyl shikimate

: 143308-74-1
(3aR,7R,7aS)-methyl 7-acetoxy-2,2-dimethyl-3a,6,7,7atetrahydrobenzo[d][1,3]dioxole-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 92 mg / Dowex-50 (H+) / acetone / 3 h / 20 °C

2: 100 percent / pyridine / 1 h / 20 °C

With pyridine; Dowex-50 (H+); In acetone;
DOI:10.1016/S0008-6215(01)00079-9

Reference yield:

: 138-59-0
shikimic acid

: 143308-74-1
(3aR,7R,7aS)-methyl 7-acetoxy-2,2-dimethyl-3a,6,7,7atetrahydrobenzo[d][1,3]dioxole-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / Amberlite IR 120 / 12 h / Heating

2: 96 percent / camphorsulfonic acid / 0.25 h / Ambient temperature

3: 100 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 2 h / Ambient temperature

With dmap; Amberlite IR 120; camphor-10-sulfonic acid; In dichloromethane;
DOI:10.1021/jo00047a049