(3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Base Information

Chemical Name:(3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole
CAS No.:17087-84-2
Molecular Formula:C12H19ClO5
Molecular Weight:278.73
Hs Code.:
European Community (EC) Number:621-145-1
Nikkaji Number:J741.667I
Mol file:17087-84-2.mol

Synonyms:17087-84-2;(3As,4R,6R,6aS)-4-chloro-6-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxole;(3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole;SCHEMBL4585348;CVRZEBFHLBJQLI-ZJDVBMNYSA-N;2,3:5,6-DI-O-ISOPROPYLIDENE-A-D-*MANNOFU RANOSYL CHL;2-O,3-O:5-O,6-O-Diisopropylidene-alpha-D-mannofuranosyl chloride

Suppliers and Price of (3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2,3:5,6-DI-O-ISOPROPYLIDENE-ALPHA-D-MANNOFURANOSYL CHLORIDE 95.00%
5MG
$ 495.41

Total 4 raw suppliers

Chemical Property of (3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Chemical Property:

PSA：46.15000
LogP:1.62170
Storage Temp.:?20°C
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:278.0921014
Heavy Atom Count:18
Complexity:345

Purity/Quality:

99% ^*data from raw suppliers

2,3:5,6-DI-O-ISOPROPYLIDENE-ALPHA-D-MANNOFURANOSYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 22-24/25-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(OCC(O1)C2C3C(C(O2)Cl)OC(O3)(C)C)C
Isomeric SMILES:CC1(OC[C@@H](O1)[C@@H]2[C@H]3[C@@H]([C@H](O2)Cl)OC(O3)(C)C)C

Technology Process of (3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

There total 17 articles about (3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 7757-38-2,14131-84-1,23262-78-4,27108-13-0,33823-04-0,34685-42-2,57819-52-0,78039-08-4,78039-12-0,78964-16-6,94842-76-9,149342-31-4
2,3,5,6-di-O-isopropylidene-D-mannofuranose

: 17087-84-2
(3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Guidance literature:: With tetrachloromethane; triphenylphosphine; In tetrahydrofuran; Inert atmosphere; Reflux;
DOI:10.1002/ejoc.200900417

Reference yield: 95.0%

: 530-26-7
D-Mannose

: 6160-67-4,16136-64-4,17087-84-2,33823-06-2,57819-53-1,67253-98-9,72258-31-2,142034-31-9
(3aS,4R,6R,6aS)-4-chloro-6-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxole

Guidance literature:: D-Mannose; With sulfuric acid; In acetone; at 0 ℃; for 0.5h; Inert atmosphere;

With pyridine; bis(trichloromethyl) carbonate; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1039/d1cc03589d