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CPo3604-01

Base Information
  • Chemical Name:CPo3604-01
  • CAS No.:951127-25-6
  • Molecular Formula:C16H19F2NO4
  • Molecular Weight:327.328
  • Hs Code.:
  • Mol file:951127-25-6.mol
CPo3604-01

Synonyms:CPo3604-01;tert-butyl [(2R,3S)-5-oxo-2-(2,5-difluorophenyl)tetradihydro-2H-pyran-3-yl]carbaMate;tert-butyl [(2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pvran-3 yl]carbaMate;tert-butyl ((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbaMate;N-[(2R,3S)-2-(2,5-difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]-CarbaMic acid 1,1-diMethylethyl ester;Product NaMe:MK-3102 interMediate;Omarigliptin inter. OG-1;Carbamic acid, N-[(2R,3S)-2-(2,5-difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]-, 1,1-dimethylethyl ester

Suppliers and Price of CPo3604-01
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • N-[(2R,3S)-2-(2,5-Difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamicAcid1,1-DimethylethylEster
  • 100mg
  • $ 140.00
  • Matrix Scientific
  • tert-ButylN-[(2R,3S)-2-(2,5-difluorophenyl)-5-oxo-tetrahydropyran-3-yl]carbamate 95+%
  • 1g
  • $ 299.00
  • Matrix Scientific
  • tert-ButylN-[(2R,3S)-2-(2,5-difluorophenyl)-5-oxo-tetrahydropyran-3-yl]carbamate 95+%
  • 500mg
  • $ 194.00
  • Labseeker
  • TERT-BUTYL ((2R,3S)-2-(2,5-DIFLUOROPHENYL)-5-OXOTETRAHYDRO-2H-PYRAN-3-YL)CARBAMATE 95
  • 1kg
  • $ 22999.00
  • Crysdot
  • tert-Butyl((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate 95+%
  • 1g
  • $ 297.00
  • Chemenu
  • tert-butyl((2R,3S)-2-(2,5-difluorophenyl)-5-oxotetrahydro-2H-pyran-3-yl)carbamate 95%
  • 100g
  • $ 2516.00
  • Biosynth Carbosynth
  • tert-Butyl (2R,3S)[2-(2,5-difluoro-phenyl)-5-oxo-tetrahydro-pyran-3-yl]-carbamate
  • 50 g
  • $ 750.00
  • Biosynth Carbosynth
  • tert-Butyl (2R,3S)[2-(2,5-difluoro-phenyl)-5-oxo-tetrahydro-pyran-3-yl]-carbamate
  • 25 g
  • $ 625.00
  • Biosynth Carbosynth
  • tert-Butyl (2R,3S)[2-(2,5-difluoro-phenyl)-5-oxo-tetrahydro-pyran-3-yl]-carbamate
  • 10 g
  • $ 450.00
  • Biosynth Carbosynth
  • tert-Butyl (2R,3S)[2-(2,5-difluoro-phenyl)-5-oxo-tetrahydro-pyran-3-yl]-carbamate
  • 5 g
  • $ 300.00
Total 96 raw suppliers
Chemical Property of CPo3604-01
Chemical Property:
  • Boiling Point:433.4±45.0 °C(Predicted) 
  • PKA:11.00±0.40(Predicted) 
  • PSA:64.63000 
  • Density:1.25±0.1 g/cm3(Predicted) 
  • LogP:3.27950 
  • Storage Temp.:2-8°C 
Purity/Quality:

99%, *data from raw suppliers

N-[(2R,3S)-2-(2,5-Difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamicAcid1,1-DimethylethylEster *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses N-[(2R,3S)-2-(2,5-Difluorophenyl)tetrahydro-5-oxo-2H-pyran-3-yl]carbamic Acid 1,1-Dimethylethyl Ester is a useful synthetic intermediate in the synthesis of Omarigliptin (O633100); a potent and selective dipeptidyl peptidase 4 (DPP-4) inhibitor used for the treatment of type 2 diabetes.
Technology Process of CPo3604-01

There total 77 articles about CPo3604-01 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In water; ethyl acetate; at 20 ℃;
Guidance literature:
With zinc(II) chloride; In ethanol; at 0 ℃; Inert atmosphere; Large scale;
Guidance literature:
With sodium periodate; ruthenium(III) chloride trihydrate; In dichloromethane; water; acetonitrile; at 25 ℃; for 3h;
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