tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate

Base Information

Chemical Name:tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate
CAS No.:345893-27-8
Molecular Formula:C11H14ClNO3
Molecular Weight:243.69
Hs Code.:2934208090
DSSTox Substance ID:DTXSID20701729
Wikidata:Q82633497
ChEMBL ID:CHEMBL4934711
Mol file:345893-27-8.mol

Synonyms:345893-27-8;tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate;tert-butyl N-(4-chloro-3-hydroxyphenyl)carbamate;(4-chloro-3-hydroxy-phenyl)-carbamic acid tert-butyl ester;TERT-BUTYL 4-CHLORO-3-HYDROXYPHENYLCARBAMATE;tert-butyl(4-chloro-3-hydroxyphenyl)carbamate;SCHEMBL5744348;CHEMBL4934711;DTXSID20701729;BWJHNIPKQFCYIS-UHFFFAOYSA-N;MFCD09951954;AKOS014116220;AS-5730;1-(Boc-amino)-4-Chloro-3-hydroxybenzene;CS-0273187;FT-0721364;F83457;EN300-1880603;A898302;4-Chloro-3-hydroxyphenylcarbamic acid tert-butyl ester

Suppliers and Price of tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
(4-Chloro-3-hydroxyphenyl)carbamic acid tert-butyl ester
500 mg
$ 303.00

Matrix Scientific
(4-Chloro-3-hydroxy-phenyl)-carbamicacidtert-butylester 95%+
500mg
$ 468.00

American Custom Chemicals Corporation
TERT-BUTYL-4-CHLORO-3-HYDROXYPHENYLCARBAMATE 95.00%
5MG
$ 503.54

Advanced Chemicals Intermediatesced Chemicals Intermediates
(4-Chloro-3-hydroxy-phenyl)-carbamicacidtert-butylester 95%+
500mg
$ 188.50

Acints
(4-Chloro-3-hydroxy-phenyl)-carbamicacidtert-butylester 95%+
1g
$ 355.25

Acints
(4-Chloro-3-hydroxy-phenyl)-carbamicacidtert-butylester 95%+
500mg
$ 188.50

Total 5 raw suppliers

Chemical Property of tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate

Chemical Property:

PSA：62.05000
LogP:3.40620
XLogP3:3.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:243.0662210
Heavy Atom Count:16
Complexity:252

Purity/Quality:

97% ^*data from raw suppliers

(4-Chloro-3-hydroxyphenyl)carbamic acid tert-butyl ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC(=C(C=C1)Cl)O

Technology Process of tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate

There total 2 articles about tert-Butyl (4-chloro-3-hydroxyphenyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 6358-06-1
5-amino-2-chlorophenol

: 345893-27-8
tert-butyl (4-chloro-3-hydroxyphenyl)carbamate

Guidance literature:: In tetrahydrofuran; Inert atmosphere; Reflux;
DOI:10.3762/bjoc.9.111

Reference yield:

: 619-10-3
5-nitro-2-chlorophenol

: 345893-27-8
tert-butyl (4-chloro-3-hydroxyphenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: Pt/C / ethyl acetate

2: tetrahydrofuran

Pt/C; In tetrahydrofuran; ethyl acetate;