2-Chloro-4-ethylthiazole

Base Information

Chemical Name:2-Chloro-4-ethylthiazole
CAS No.:98025-12-8
Molecular Formula:C₅H₆ClNS
Molecular Weight:147.628
Hs Code.:2934100090
DSSTox Substance ID:DTXSID20477497
Wikidata:Q82310243
Mol file:98025-12-8.mol

Synonyms:2-Chloro-4-ethylthiazole;98025-12-8;2-chloro-4-ethyl-1,3-thiazole;Thiazole,2-chloro-4-ethyl-;SCHEMBL1990600;DTXSID20477497;YDA02512;MFCD16817473;AKOS012241164;AT27375;BS-29859;CS-0211308;EN300-66378;A858595;Z1037582854

Suppliers and Price of 2-Chloro-4-ethylthiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-4-ethylthiazole
50mg
$ 90.00

SynQuest Laboratories
2-Chloro-4-ethylthiazole 95%
1 g
$ 680.00

SynQuest Laboratories
2-Chloro-4-ethylthiazole 95%
100 mg
$ 192.00

SynQuest Laboratories
2-Chloro-4-ethylthiazole 95%
250 mg
$ 336.00

Crysdot
2-Chloro-4-ethylthiazole 95+%
1g
$ 325.00

Crysdot
2-Chloro-4-ethylthiazole 95+%
5g
$ 923.00

Chemenu
2-chloro-4-ethylthiazole 95%
5g
$ 870.00

Chemenu
2-chloro-4-ethylthiazole 95%
1g
$ 307.00

Apolloscientific
2-Chloro-4-ethylthiazole 95%
250mg
$ 210.00

Apolloscientific
2-Chloro-4-ethylthiazole 95%
100mg
$ 120.00

Total 10 raw suppliers

Chemical Property of 2-Chloro-4-ethylthiazole

Chemical Property:

Boiling Point:56 °C(Press: 5 Torr)
PKA:1.42±0.10(Predicted)
PSA：41.13000
Density:1.262±0.06 g/cm3(Predicted)
LogP:2.35890
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:146.9909481
Heavy Atom Count:8
Complexity:78.8

Purity/Quality:

97% ^*data from raw suppliers

2-Chloro-4-ethylthiazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CSC(=N1)Cl

Technology Process of 2-Chloro-4-ethylthiazole

There total 1 articles about 2-Chloro-4-ethylthiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3028-74-8
thiocyanic acid, 2-oxobutyl ester

: 98025-12-8
2-chloro-4-ethylthiazole

Guidance literature:: With hydrogenchloride;

Reference yield:

: 98025-12-8
2-chloro-4-ethylthiazole

: 2-chloro-4-ethylthiazole-5-sulfonyl chloride

Guidance literature:: With chlorosulfonic acid; thionyl chloride; at 120 ℃; for 48h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.7b00183

Reference yield:

: 98025-12-8
2-chloro-4-ethylthiazole

: N-(4-ethyl-5-sulfamoylthiazol-2-yl)-N-methyl-2-(4-(pyridin-2-yl)phenyl)acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride; chlorosulfonic acid / 48 h / 120 °C / Inert atmosphere

2: 0 - 20 °C / Inert atmosphere

3: acetonitrile / 50 °C / Inert atmosphere

4: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With chlorosulfonic acid; thionyl chloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/acs.jmedchem.7b00183