Thiocyanic acid, 2-oxobutyl ester

Base Information

• Chemical Name: Thiocyanic acid, 2-oxobutyl ester
• CAS No.: 3028-74-8
• Molecular Formula: C5H7NOS
• Mol file: 3028-74-8.mol

Synonyms:

Chemical Property of Thiocyanic acid, 2-oxobutyl ester

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Thiocyanic acid, 2-oxobutyl ester

There total 1 articles about Thiocyanic acid, 2-oxobutyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilyl cyanide (7677-24-9) + butanone (78-93-3) → thiocyanic acid, 2-oxobutyl ester (3028-74-8) + 3-thiocyanobutan-2-one (57308-65-3)

Guidance literature:

With sulfur; In dimethyl sulfoxide; at 50 ℃; for 24h; Overall yield = 72 percent; Overall yield = 27.9 mg; regioselective reaction; Schlenk technique; Sealed tube;

DOI:10.1021/acs.joc.1c02431

Reference yield:

thiocyanic acid, 2-oxobutyl ester (3028-74-8) → 5-Ethyl-thiazolin-thion(2) (33120-75-1)

Guidance literature:

With ethanol; hydrogen sulfide; under 205942 Torr;

Reference yield:

thiocyanic acid, 2-oxobutyl ester (3028-74-8) → 2-chloro-4-ethylthiazole (98025-12-8)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

trimethylsilyl cyanide

butanone

Downstream raw materials:

2-chloro-4-ethylthiazole

5-Ethyl-thiazolin-thion(2)

Refernces