BENZOIC ACID-CARBOXY-14C

Base Information

• Chemical Name: BENZOIC ACID-CARBOXY-14C
• CAS No.: 1589-66-8
• Molecular Formula: C7H6O2
• Molecular Weight: 124.112
• Mol file: 1589-66-8.mol

Synonyms:C6H5 14COOH;[CARBOXYL-14C]BENZOIC ACID;BENZOIC ACID-CARBOXY-14C;benzoic acid-carboxy-14C toluene*solution;BENZOIC ACID-CARBOXY-14C*ACETONE SOLUTIO N;BENZOIC ACID-CARBOXY-14C TOULENE*SOLUTIO N

Chemical Property of BENZOIC ACID-CARBOXY-14C

Chemical Property:

• PSA: 37.30000
• LogP: 1.38480
• Storage Temp.: 2-8°C

Purity/Quality:

99%min ^*data from raw suppliers

BENZOIC ACID[7-14C] 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,R,F
• Hazard Codes: Xn,R,F
• Statements: 22-36-42/43-20/21/22-11
• Safety Statements: 26-36-16

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BENZOIC ACID-CARBOXY-14C

There total 6 articles about BENZOIC ACID-CARBOXY-14C which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

[14C]carbon dioxide (51-90-1) + phenyllithium (591-51-5) → [carbonyl-(14)C]benzoic acid (1589-66-8)

Guidance literature:

DOI:10.1002/(SICI)1099-1344(199711)39:11<907::AID-JLCR38>3.0.CO;2-2

Reference yield: 80.0%

iodobenzene (591-50-4) + [14C]carbon dioxide (51-90-1) → [carbonyl-(14)C]benzoic acid (1589-66-8)

Guidance literature:

With sulfuric acid; potassium acetate; lithium triethylborohydride; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; dimethyl sulfoxide; at 85 ℃; for 15h;

DOI:10.1002/1099-1344(20001015)43:11<1135::AID-JLCR404>3.0.CO;2-T

Reference yield: 78.0%

bromobenzene (108-86-1,52753-63-6) + lithium [14C]formate → [carbonyl-(14)C]benzoic acid (1589-66-8)

Guidance literature:

With formic acid; sulfuric acid; potassium acetate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In water; dimethyl sulfoxide; at 70 ℃; for 16h;

DOI:10.1002/1099-1344(20001015)43:11<1135::AID-JLCR404>3.0.CO;2-T

upstream raw materials:

[14C]carbon dioxide

phenyllithium

phenylmagnesium chloride

bromobenzene

Downstream raw materials:

[carboxyl-14C]-methyl benzoate

4-[1-methyl-2,4-dioxo-6-(3-phenylprop-1-yn-1-yl)-1,4-dihydro-2H-quinazolin-3-ylmethyl]benzoic acid

4-[1-methyl-2,4-dioxo-6-(3-phenyl-[3-¹⁴C]prop-1-ynyl)-1,4-dihydro-2Hquinazolin-3-ylmethyl]benzoic acid

[3-¹⁴C]1-triphenylsilyl-3-phenylpropyne