2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Base Information

Chemical Name:2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid
CAS No.:154365-40-9
Molecular Formula:C10H9NO4
Molecular Weight:207
Hs Code.:2934999090
DSSTox Substance ID:DTXSID20392136
Mol file:154365-40-9.mol

Synonyms:154365-40-9;2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid;2-methyl-3-oxo-4H-1,4-benzoxazine-2-carboxylic acid;3,4-Dihydro-2-methyl-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid;2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylic acid;SCHEMBL8630183;DTXSID20392136;HNDTULADLKGMDH-UHFFFAOYSA-N;MFCD04124544;AKOS005069689;CS-0213389;EN300-316147;F10446;SR-01000307059;12W-0216;J-509961;SR-01000307059-1;Z1508938218;2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid;2-Methyl-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-2-carboxylic acid, AldrichCPR

Suppliers and Price of 2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methyl-3-oxo-3,4-dihydro-2h-1,4-benzoxazine-2-carboxylicAcid
50mg
$ 45.00

TRC
2-Methyl-3-oxo-3,4-dihydro-2h-1,4-benzoxazine-2-carboxylicAcid
500mg
$ 155.00

SynQuest Laboratories
3,4-Dihydro-2-methyl-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid
1 g
$ 103.00

Matrix Scientific
2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid >95%
5g
$ 698.00

Matrix Scientific
2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid >95%
500mg
$ 110.00

Matrix Scientific
2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid >95%
1g
$ 170.00

Crysdot
2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid 95+%
5g
$ 339.00

Crysdot
2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid 95+%
10g
$ 489.00

Chemenu
2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid 95%
10g
$ 462.00

Chemenu
2-Methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-2-carboxylicacid 95%
5g
$ 320.00

Total 8 raw suppliers

Chemical Property of 2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

Chemical Property:

Melting Point:192～194℃
PSA：75.63000
LogP:0.99880
XLogP3:1.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:207.05315777
Heavy Atom Count:15
Complexity:304

Purity/Quality:

98%min ^*data from raw suppliers

2-Methyl-3-oxo-3,4-dihydro-2h-1,4-benzoxazine-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(=O)NC2=CC=CC=C2O1)C(=O)O

Technology Process of 2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid

There total 2 articles about 2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 154365-33-0
3,4-dihydro-2-methyl-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid ethyl ester

: 154365-40-9
3,4-dihydro-2-methyl-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; for 18h; Ambient temperature;
DOI:10.1002/jhet.5570300303

Reference yield:

: 95-55-6
2-amino-phenol

: 154365-40-9
3,4-dihydro-2-methyl-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 81 percent / KF / dimethylformamide / 6 h / 60 °C

2: 80 percent / 1N NaOH / dioxane / 18 h / Ambient temperature

With potassium fluoride; sodium hydroxide; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570300303