1-(2-Amino-4-chloro-5-fluorophenyl)ethanone

Base Information

Chemical Name:1-(2-Amino-4-chloro-5-fluorophenyl)ethanone
CAS No.:937816-87-0
Molecular Formula:C8H7ClFNO
Molecular Weight:187.601
Hs Code.:2922399090
DSSTox Substance ID:DTXSID30585310
Wikidata:Q82477227
Mol file:937816-87-0.mol

Synonyms:1-(2-amino-4-chloro-5-fluorophenyl)ethanone;937816-87-0;1-(2-AMINO-4-CHLORO-5-FLUOROPHENYL)ETHAN-1-ONE;2'-Amino-4'-chloro-5'-fluoroacetophenone;SCHEMBL21232254;DTXSID30585310;AKOS006306171;CS-0272061;EN300-672886;Q-101061

Suppliers and Price of 1-(2-Amino-4-chloro-5-fluorophenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(2-Amino-4-chloro-5-fluorophenyl)ethanone 95+%
1g
$ 455.00

Chemcia Scientific
1-(2-Amino-4-chloro-5-fluoro-phenyl)-ethanone 95%
1 G
$ 495.00

Chemcia Scientific
1-(2-Amino-4-chloro-5-fluoro-phenyl)-ethanone 95%
0.5 G
$ 345.00

American Custom Chemicals Corporation
1-(2-AMINO-4-CHLORO-5-FLUOROPHENYL)ETHANONE 95.00%
5MG
$ 500.57

Alichem
1-(2-Amino-4-chloro-5-fluorophenyl)ethanone
1g
$ 409.20

Total 6 raw suppliers

Chemical Property of 1-(2-Amino-4-chloro-5-fluorophenyl)ethanone

Chemical Property:

Vapor Pressure:0.000237mmHg at 25°C
Boiling Point:325°C at 760 mmHg
Flash Point:150.4°C
PSA：43.09000
Density:1.345g/cm³
LogP:2.84510
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:187.0200197
Heavy Atom Count:12
Complexity:188

Purity/Quality:

97% ^*data from raw suppliers

1-(2-Amino-4-chloro-5-fluorophenyl)ethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1N)Cl)F

Technology Process of 1-(2-Amino-4-chloro-5-fluorophenyl)ethanone

There total 2 articles about 1-(2-Amino-4-chloro-5-fluorophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 97674-02-7
tributyl(1-ethoxyvinyl)stannane

: 85462-59-5
2-bromo-5-chloro-4-fluoroaniline

: 937816-87-0
1-(2-amino-4-chloro-5-fluorophenyl)ethanone

Guidance literature:: tributyl(1-ethoxyvinyl)stannane; 2-bromo-5-chloro-4-fluoroaniline; With bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; at 100 ℃; for 12h; Inert atmosphere;

With hydrogenchloride; In water; N,N-dimethyl-formamide; at 25 ℃; for 3h; Temperature;

Reference yield:

: 367-21-5
3-chloro-4-fluorophenylamine

: 75-05-8,26809-02-9
acetonitrile

: 937816-87-0
1-(2-amino-4-chloro-5-fluorophenyl)ethanone

Guidance literature:: 3-chloro-4-fluorophenylamine; acetonitrile; With boron trichloride; In n-heptane;

With aluminium trichloride; In n-heptane; Heating;

With hydrogenchloride; In n-heptane; Further stages.; Heating;
DOI:10.1021/jm061428x