5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole

Base Information

Chemical Name:5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole
CAS No.:326602-80-6
Molecular Formula:C₁₇H₁₉N₃O₃S
Molecular Weight:345.422
Hs Code.:
Mol file:326602-80-6.mol

Synonyms:1H-Benzimidazole, 5-methoxy-2-((S)-((4-methoxy-3,5-dimethyl-2- pyridinyl)methyl)sulfinyl)-;Nexiam;Unii-N3pa6559ft

Suppliers and Price of 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ESOMEPRAZOLE 95.00%
10MG
$ 610.02

American Custom Chemicals Corporation
ESOMEPRAZOLE 95.00%
1MG
$ 590.61

Total 13 raw suppliers

Chemical Property of 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole

Chemical Property:

PSA：96.31000
LogP:3.76540

Purity/Quality:

99% ^*data from raw suppliers

ESOMEPRAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole

There total 24 articles about 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]-3H-benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: (6-methoxy-1H-benzo[d]imidazol-2-yl)boronic acid

: (4-methoxy-3,5-dimethylpyridin-2-yl)methanesulfinyl chloride

: 73590-58-6,326602-80-6
omeprazole

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,4-dioxane; at 60 ℃; for 4h; Reagent/catalyst; Temperature; Inert atmosphere;

Reference yield: 86.6%

: 73590-85-9
6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole

: 73590-58-6,326602-80-6
omeprazole

Guidance literature:: With dihydrogen peroxide; triethylamine; In water; isopropyl alcohol; at 0 ℃; chemoselective reaction;
DOI:10.1039/b912521n

Reference yield: 82.0%

: 73590-85-9
6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole

: 119141-88-7,326602-80-6
(S)-6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]-sulfinyl]-1H-benzimidazole

: 119141-89-8,326602-80-6
(R)-6-methoxy-2-((4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl)-1H-benzoimidazole

Guidance literature:: 6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole; With bis(acetylacetonate)oxovanadium; C₂₂H₃₃NO₂; N-ethyl-N,N-diisopropylamine; at 0 - 5 ℃;

With Cumene hydroperoxide; In Isopropylbenzene; for 6h; optical yield given as %ee;
DOI:10.1007/s11172-008-0221-6