2-(4-Chloro-phenyl)-pyriMidine-5-carboxylic acid ethyl ester

Base Information

Chemical Name:2-(4-Chloro-phenyl)-pyriMidine-5-carboxylic acid ethyl ester
CAS No.:304693-58-1
Molecular Formula:C13H11ClN2O2
Molecular Weight:262.696
Hs Code.:2933599090
Mol file:304693-58-1.mol

Synonyms:2-(4-Chloro-phenyl)-pyriMidine-5-carboxylic acid ethyl ester;ethyl 2-(4-chlorophenyl)pyriMidine-5-carboxylate

Suppliers and Price of 2-(4-Chloro-phenyl)-pyriMidine-5-carboxylic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl2-(4-chlorophenyl)pyrimidine-5-carboxylate 95+%
1g
$ 550.00

Chemenu
Ethyl2-(4-chlorophenyl)pyrimidine-5-carboxylate 95%
1g
$ 519.00

Alichem
Ethyl2-(4-chlorophenyl)pyrimidine-5-carboxylate
1g
$ 585.00

Total 3 raw suppliers

Chemical Property of 2-(4-Chloro-phenyl)-pyriMidine-5-carboxylic acid ethyl ester

Chemical Property:

PSA：52.08000
LogP:2.97370

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-(4-chlorophenyl)pyrimidine-5-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-(4-Chloro-phenyl)-pyriMidine-5-carboxylic acid ethyl ester

There total 4 articles about 2-(4-Chloro-phenyl)-pyriMidine-5-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 304693-56-9
ethyl 2-(4-chlorophenyl)-4-chloropyrimidine-5-carboxylate

: 304693-58-1
ethyl 2-(4-chlorophenyl)pyrimidine-5-carboxylate

Guidance literature:: ethyl 2-(4-chlorophenyl)-4-chloropyrimidine-5-carboxylate; With zinc; In tetrahydrofuran; acetic acid; at 60 ℃; for 18h;

With zinc; In acetic acid; for 24h;

Reference yield:

: 56406-33-8
eEthyl 2-(4-chlorophenyl)-4-oxopyrimidine-5-carboxylate

: 304693-58-1
ethyl 2-(4-chlorophenyl)pyrimidine-5-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride / dichloromethane / 3 h / 20 °C / Cooling with ice

2: zinc; acetic acid / tetrahydrofuran / 42 h / 60 °C

With oxalyl dichloride; acetic acid; zinc; In tetrahydrofuran; dichloromethane;

Reference yield:

: 37555-99-0
diethyl ethoxymalonate

: 304693-58-1
ethyl 2-(4-chlorophenyl)pyrimidine-5-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium ethanolate / ethanol / 4 h / Reflux

2: oxalyl dichloride / dichloromethane / 3 h / 20 °C / Cooling with ice

3: zinc; acetic acid / tetrahydrofuran / 42 h / 60 °C

With oxalyl dichloride; sodium ethanolate; acetic acid; zinc; In tetrahydrofuran; ethanol; dichloromethane;